(Bromomethyl)cyclopropane
- CAS No.7051-34-5
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
Premium grade (Bromomethyl)cyclopropane CAS 7051-34-5 designed for complex pharmaceutical synthesis and organic building block applications.
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Product Overview
(Bromomethyl)cyclopropane is a highly specialized organic intermediate characterized by its cyclopropane ring structure and reactive bromomethyl group. This chemical building block is essential for modern pharmaceutical synthesis, offering unique reactivity profiles for constructing complex molecular architectures. Our facility produces this compound under strict quality control standards to ensure consistency for downstream industrial applications.
As a key reagent in organic chemistry, this substance serves as a vital precursor in the manufacturing of various therapeutic agents. The stability of the cyclopropane ring combined with the leaving group capability of the bromine atom makes it an invaluable tool for medicinal chemists and process engineers alike.
Physical and Chemical Properties
This compound presents as a colorless to yellowish liquid under standard conditions. It possesses distinct physical properties that facilitate its handling in industrial synthesis reactors. The molecular formula C4H7Br corresponds to a molecular weight of approximately 135.00 g/mol. Key physical constants include a density of 1.392 g/cm3 and a boiling point range between 105 and 107 degrees Celsius. The flash point is recorded at 107 degrees Fahrenheit, requiring standard safety precautions during storage and transport.
The refractive index is measured at 1.457, serving as a critical parameter for identity confirmation during quality assurance testing. These physical characteristics are consistent across batches, ensuring reliable performance in chemical reactions such as alkylation and nucleophilic substitution.
Quality Specifications
We adhere to rigorous factory standards to guarantee high purity levels suitable for sensitive pharmaceutical applications. Each batch undergoes comprehensive analysis using gas chromatography and moisture detection methods. The following table outlines the typical specification profile:
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | Colorless to yellowish liquid | Conform |
| Purity (GC) | Greater than or equal to 98.0 percent | 98.5 percent |
| Moisture | Less than or equal to 0.5 percent | 0.06 percent |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
The primary application of (Bromomethyl)cyclopropane lies in the synthesis of advanced pharmaceutical intermediates. It is utilized in the production pathways for several notable therapeutic agents, including cardiovascular and respiratory medications. Its role as an alkylating agent allows for the precise introduction of cyclopropylmethyl groups into target molecules.
Common uses include the synthesis of intermediates for Betaxolol and Roflumilast. The high purity ensures minimal byproduct formation during subsequent reaction steps, optimizing overall yield and reducing purification costs. This material is also applicable in broader organic synthesis contexts where cyclopropane derivatives are required for structure-activity relationship studies.
Storage and Handling
Proper storage is critical to maintain the integrity of this chemical product. It should be stored in a cool, ventilated place away from direct sunlight and heat sources. Containers must remain tightly sealed to prevent moisture absorption and potential degradation. We recommend using standard chemical storage protocols compatible with halogenated organic compounds.
Handling should be performed in a well-ventilated area with appropriate personal protective equipment. In case of spillage, standard absorbent materials should be used followed by proper disposal according to local environmental regulations. Our logistics team ensures secure packaging to prevent leakage during transit.
Commitment to Quality
As a global manufacturer, we prioritize consistency and reliability. Every shipment is accompanied by a Certificate of Analysis (COA) verifying compliance with specified parameters. We offer flexible packaging options, including 25 kg drums or custom configurations based on client requirements. Our technical support team is available to assist with integration into your manufacturing processes.
