Intermediates

Chlorotriphenylsilane

  • CAS No.76-86-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Chlorotriphenylsilane (CAS 76-86-8) designed for pharmaceutical intermediate synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

Chlorotriphenylsilane is a premier organosilicon compound widely recognized for its versatility in organic synthesis and pharmaceutical manufacturing. As a key building block, this reagent facilitates the introduction of triphenylsilyl protecting groups, enhancing the stability and selectivity of complex molecular structures. Our manufacturing process ensures exceptional consistency, making it an ideal choice for research laboratories and industrial-scale production facilities requiring high-performance chemical inputs.

We are committed to delivering products that meet rigorous international standards. Each batch undergoes comprehensive analytical testing to verify purity and structural integrity. This dedication to quality ensures that downstream synthesis processes proceed smoothly, minimizing impurities and maximizing yield efficiency in the production of advanced pharmaceutical intermediates.

Key Specifications

ParameterValue
Product NameChlorotriphenylsilane
CAS Number76-86-8
Molecular FormulaC18H15ClSi
Molecular Weight294.85
Purity≥99.0%
AppearanceWhite crystal

Physical and Chemical Properties

Understanding the physicochemical profile of Chlorotriphenylsilane is essential for safe handling and optimal application. The compound exhibits a density of 1.14 g/cm³, indicating a relatively heavy molecular structure typical of organosilicon derivatives. Its melting point ranges between 91°C and 94°C, while the boiling point is approximately 378°C, reflecting high thermal stability under standard atmospheric conditions.

The flash point is recorded at 200°C, which necessitates standard safety precautions during storage and transport to prevent ignition sources. Additionally, the refractive index of 1.495 serves as a critical quality control metric for verifying identity and purity during incoming inspection. These properties collectively define the operational window for using this reagent in various synthetic pathways.

Industrial Applications

The primary application of Chlorotriphenylsilane lies in the synthesis of pharmaceutical intermediates. It acts as a robust silylating agent, protecting hydroxyl or amino groups during multi-step organic synthesis. This protection strategy is vital for preventing unwanted side reactions, thereby ensuring the fidelity of the final active pharmaceutical ingredient (API).

  • Protection group chemistry in complex molecule synthesis.
  • Manufacture of specialized organic intermediates.
  • Research and development in organosilicon chemistry.
  • Custom synthesis projects requiring high-purity silane reagents.

Packaging and Storage

To maintain product integrity, Chlorotriphenylsilane is packaged in 25 kg drums. Custom packaging solutions are available upon request to accommodate specific logistical requirements or bulk order volumes. Proper storage is critical; the material should be kept in a cool, ventilated area away from moisture and direct sunlight. Exposure to humidity can lead to hydrolysis, so containers must remain tightly sealed when not in use.

Quality Assurance and Safety

Our quality assurance framework includes strict adherence to Good Manufacturing Practices (GMP). Every shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. We prioritize safety and compliance, ensuring that all products are handled and transported according to relevant hazardous material regulations. For technical support or safety data sheets (SDS), our expert team is available to assist with any inquiries regarding application or handling protocols.