Cytosine

Product Overview

Cytosine is a fundamental pyrimidine nucleobase widely utilized as a critical building block in the pharmaceutical industry. With a molecular formula of C4H5N3O and a molecular weight of 111.10 g/mol, this high-purity compound serves as an essential intermediate in the synthesis of nucleoside analogs used in modern antiviral and oncology therapeutics.

Specifications

Industrial Applications

Cytosine is primarily employed as a chemical intermediate in the large-scale production of several high-value pharmaceutical agents. Its core utility lies in the synthesis of nucleoside reverse transcriptase inhibitors and antimetabolite drugs, including:

• Lamivudine – a cornerstone antiviral used in the treatment of HIV/AIDS and chronic hepatitis B
• Gemcitabine – a potent chemotherapeutic agent for pancreatic, breast, and non-small cell lung cancers
• 5-Fluorocytosine – an antifungal prodrug activated by fungal enzymes
• Enoxacin derivatives – where cytosine scaffolds contribute to quinolone-based antibacterial frameworks

As a foundational heterocyclic compound, cytosine enables efficient construction of modified nucleosides through regioselective functionalization at the N1, C4, or C5 positions. Our industrial-grade material meets stringent quality benchmarks required for GMP-compliant active pharmaceutical ingredient (API) manufacturing.

Handling and Storage

Store in a cool, dry, and well-ventilated area away from direct sunlight and moisture. Keep container tightly sealed to prevent hygroscopic uptake. Standard industrial hygiene practices are recommended during handling.