Intermediates

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

  • CAS No.103733-65-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (CAS 103733-65-9) serves as a critical chiral building block for pharmaceutical intermediate synthesis, available in bulk quantities with full documentation.

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Product Technical Details

Product Overview

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is a specialized chiral organic compound widely recognized for its significance in medicinal chemistry and advanced pharmaceutical synthesis. As a key intermediate, this substance provides a robust structural foundation for the development of complex bioactive molecules. Our manufacturing process ensures exceptional stereochemical purity, making it an ideal choice for researchers and industrial partners focused on high-quality drug discovery pipelines.

The compound features a tetrahydroisoquinoline backbone with a carboxylic acid functional group at the third position, offering versatile reactivity for further chemical modifications. Its specific D-configuration (or R-enantiomer) is crucial for maintaining the biological activity of downstream products, particularly in the synthesis of peptidomimetics and enzyme inhibitors.

Technical Specifications

We adhere to strict quality control protocols to guarantee consistency across every batch. The following table outlines the key physicochemical properties and purity standards associated with this product.

ParameterSpecification
CAS Number103733-65-9
Molecular FormulaC10H11NO2
Molecular Weight177.20 g/mol
AppearanceWhite powder
Assay (Purity)≥98.0%
Boiling Point372.0±42.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Storage Condition2-8°C

Industrial Applications

This chemical intermediate is primarily utilized in the pharmaceutical sector as a building block for synthesizing novel therapeutic agents. Its structural characteristics allow it to serve as a core scaffold in the creation of amino acid derivatives and heterocyclic compounds. Common applications include the development of neurological therapeutics and cardiovascular medications where chiral integrity is paramount.

  • Pharmaceutical intermediate synthesis for complex APIs.
  • Chiral building block for peptide mimetics.
  • Research and development in medicinal chemistry.
  • Production of specialized organic compounds.

Quality Assurance and Packaging

Every shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with stated specifications. We employ advanced analytical techniques, including HPLC and NMR, to confirm identity and purity levels. Packaging is designed to maintain stability during transit, typically available in 25kg drums or customized according to client requirements. Proper storage in a cool, dry, and well-ventilated area is recommended to preserve product integrity.

Global Supply and Support

As a dedicated manufacturer, we offer competitive bulk pricing and reliable global logistics solutions. Our technical team is available to provide synthesis route guidance and support for scale-up processes. We are committed to fostering long-term partnerships through consistent quality, transparent communication, and adherence to international safety standards.