Intermediates

Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate

  • CAS No.144689-94-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of antihypertensive agents. Available in bulk quantities with full documentation.

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Product Technical Details

Product Overview

Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate represents a critical building block in modern pharmaceutical synthesis, specifically designed for the construction of complex angiotensin II receptor blocker structures. This organic compound features a robust imidazole core substituted with propyl and dicarboxylate groups, providing the necessary chemical reactivity for downstream coupling reactions. Our manufacturing process ensures consistent molecular integrity, making it an ideal choice for research laboratories and large-scale production facilities focused on cardiovascular therapeutic development.

As a specialized chemical entity, this intermediate undergoes rigorous purification protocols to eliminate trace impurities that could affect subsequent synthetic steps. The structural stability of the diethyl ester groups allows for versatile manipulation under controlled conditions, facilitating efficient route synthesis for active pharmaceutical ingredients. We prioritize batch-to-batch consistency to support our partners in maintaining regulatory compliance throughout their supply chains.

Technical Specifications

Quality control is paramount in the production of pharmaceutical intermediates. Each batch is analyzed using advanced chromatographic and spectroscopic methods to verify identity and purity levels. The physical properties listed below reflect our standard commercial grade specifications, which can be customized upon request to meet specific project requirements.

ParameterSpecification
CAS Number144689-94-1
Molecular FormulaC12H18N2O4
Molecular Weight254.28 g/mol
AppearanceWhite or off-white crystalline powder
PurityGreater than or equal to 99 percent
Melting Point86 degrees Celsius
Boiling Point400.9 degrees Celsius at 760 mmHg
Density1.16 g/cm3
Moisture ContentLess than or equal to 1.0 percent

Industrial Applications

This compound serves primarily as a key precursor in the manufacturing of antihypertensive medications. Its specific substitution pattern enables the formation of essential bonds required for the final drug molecule architecture. Pharmaceutical companies utilize this intermediate to streamline their production workflows, reducing overall synthesis time while maximizing yield efficiency. Beyond cardiovascular applications, the chemical structure offers potential utility in developing novel heterocyclic compounds for various therapeutic areas.

Researchers value this material for its predictable reactivity profile, which simplifies process optimization during scale-up phases. Whether used in medicinal chemistry campaigns or process development, the high purity level minimizes the need for extensive downstream purification, thereby reducing production costs and environmental waste. Our technical team supports clients in integrating this intermediate into their existing synthetic routes effectively.

Quality Assurance and Storage

To maintain optimal stability, the product is packaged in sealed containers that protect against moisture and light exposure. We recommend storage in a cool, dry environment with adequate ventilation to preserve chemical properties over extended periods. Each shipment includes a comprehensive Certificate of Analysis detailing test results against established specifications. Our quality management system adheres to international standards, ensuring traceability from raw material sourcing to final dispatch.

Why Choose Our Supply

  • Consistent high purity levels suitable for GMP manufacturing
  • Scalable production capacity to meet global demand
  • Comprehensive technical support and documentation
  • Competitive pricing structures for bulk orders
  • Reliable logistics and secure packaging solutions