Intermediates

Diethyl Chlorophosphate

  • CAS No.814-49-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Diethyl Chlorophosphate (CAS 814-49-3), a key organophosphorus intermediate for agrochemical synthesis.

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Product Technical Details

Product Overview

Diethyl Chlorophosphate (CAS 814-49-3) is a critical organophosphorus compound widely employed as a chemical intermediate in the synthesis of specialized agrochemicals. This reagent features high reactivity and selectivity, making it indispensable in the construction of phosphonate and phosphate-based molecular architectures. Supplied in ≥98.0% assay purity, it meets stringent industrial standards for consistent performance in large-scale manufacturing environments.

Specifications

Molecular FormulaC₄H₁₀ClO₃P
Molecular Weight172.55 g/mol
Density1.2 ± 0.1 g/cm³
Boiling Point217.2 ± 0.0 °C at 760 mmHg
Flash Point61.1 ± 0.0 °C
Vapour Density5.94 (vs air)
Refractive Index1.415
AppearanceColourless to light yellow liquid
Assay≥98.0%

Industrial Applications

Diethyl Chlorophosphate serves primarily as a building block in the production of organophosphate pesticides. It is a documented intermediate in the synthesis of Phosfolan (CAS 947-02-4) and Mephosfalan (CAS 950-10-7)—compounds historically used in agricultural pest control formulations. Its role involves phosphorylation and chlorination steps that enable the introduction of ethoxyphosphoryl moieties into complex organic frameworks.

Key advantages of this intermediate include:

  • High functional group compatibility in multi-step syntheses
  • Controlled reactivity under anhydrous conditions
  • Scalable handling in standard chemical manufacturing infrastructure

For safe handling, store in a cool, well-ventilated area away from moisture, heat sources, and incompatible materials such as strong bases or nucleophiles. Standard packaging is 25 kg drums, with custom configurations available upon request.