Intermediates

Diethyl (hydroxymethyl)phosphonate

  • CAS No.3084-40-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Diethyl (hydroxymethyl)phosphonate (CAS 3084-40-0) is a key liquid intermediate for antiviral pharmaceutical synthesis, available in bulk quantities with full documentation.

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Product Technical Details

Product Overview

Diethyl (hydroxymethyl)phosphonate is a specialized organophosphorus compound widely recognized for its critical role in modern pharmaceutical chemistry. As a versatile phosphonate ester, this substance serves as an essential building block in the construction of complex nucleotide analogues. Our facility produces this chemical under strict quality control standards to ensure consistency and reliability for large-scale industrial applications. The presence of the hydroxymethyl group alongside the phosphonate functionality makes it particularly valuable for introducing phosphonate moieties into organic structures during multi-step synthesis pathways.

We understand the demanding requirements of the pharmaceutical industry. Therefore, our manufacturing process focuses on achieving high chemical purity and minimizing impurities that could affect downstream reactions. This product is supplied as a clear liquid, facilitating easy handling and integration into various solvent systems used in organic synthesis laboratories and production plants.

Technical Specifications

Our commitment to quality is reflected in the rigorous testing performed on every batch. The following table outlines the key physical and chemical properties typically associated with our premium grade material.

ParameterSpecification
CAS Number3084-40-0
Molecular FormulaC5H13O4P
Molecular Weight168.13 g/mol
AppearanceColorless to yellow liquid
Purity≥99.0%
Density1.14 g/mL at 25 °C
Boiling Point124-126 °C at 3 mm Hg
Refractive Index1.444
Flash Point>230 °F

Industrial Applications

This phosphonate derivative is primarily utilized as a strategic intermediate in the synthesis of antiviral medications. It plays a pivotal role in the production chain for nucleotide analogues, which are fundamental to treating various viral infections. Specifically, it acts as a precursor in the manufacturing of agents such as Adefovir dipivoxil. The chemical stability and reactivity profile of Diethyl (hydroxymethyl)phosphonate allow chemists to efficiently construct the necessary phosphonate ester bonds required for biological activity in the final drug substance.

Beyond antiviral therapeutics, this compound finds utility in broader organic synthesis contexts where phosphonate chemistry is required. Researchers and process chemists value this material for its reliability in forming carbon-phosphorus bonds, enabling the development of new chemical entities and improved synthetic routes for existing pharmaceuticals.

Quality Assurance and Storage

To maintain the integrity of the product, we recommend storing Diethyl (hydroxymethyl)phosphonate in a tightly closed container within a cool, dry, and well-ventilated area. It is crucial to keep the material away from incompatible substances such as strong oxidizing agents. Our packaging options include 25kg cardboard drums or customized solutions based on specific customer logistics requirements. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with stated specifications.

Why Choose Our Facility

  • Consistent supply chain capable of meeting bulk industrial demands.
  • Advanced manufacturing processes ensuring high purity levels.
  • Comprehensive technical support and documentation provided.
  • Competitive pricing structures for long-term partnerships.
  • Global shipping capabilities with secure packaging standards.

Partnering with us ensures access to a reliable source of high-quality chemical intermediates. We are dedicated to supporting the pharmaceutical and chemical industries with products that meet the highest standards of safety and efficacy.