Intermediates

Difluoroacetic Acid

  • CAS No.381-73-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Difluoroacetic Acid suitable for pharmaceutical and agrochemical synthesis. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

Difluoroacetic Acid is a vital fluorinated organic compound widely recognized for its significance in modern chemical synthesis. As a key building block, this substance plays an essential role in the development of advanced pharmaceuticals, agrochemicals, and novel materials. The presence of two fluorine atoms on the alpha carbon imparts unique electronic properties, making it an invaluable reagent for modifying metabolic stability and bioactivity in complex molecular structures. Our commitment to excellence ensures that every batch meets rigorous international standards for purity and performance.

In the realm of organic chemistry, fluorinated intermediates are increasingly demanded due to their ability to enhance the lipophilicity and binding affinity of drug candidates. Difluoroacetic Acid serves as a precursor for various difluoroethyl groups, which are critical in designing next-generation therapeutics. We provide this chemical with a focus on consistency and reliability, supporting research and production scales alike.

Technical Specifications

Quality control is paramount in the production of fine chemicals. Our manufacturing process employs advanced fluorination technologies to ensure high purity and minimal impurities. The following table outlines the key physical and chemical properties of our standard grade product.

ParameterValue
CAS Number381-73-7
Molecular FormulaC2H2F2O2
Molecular Weight96.03 g/mol
AppearanceColorless to light yellow transparent liquid
Density1.526 g/mL at 25 °C
Boiling Point132-134 °C
Melting Point-1 °C
Refractive Indexn20/D 1.344
Flash Point174 °F

Industrial Applications

The versatility of Difluoroacetic Acid extends across multiple high-value industries. In pharmaceutical research and development, it is utilized to introduce fluorine motifs that improve the pharmacokinetic profiles of active pharmaceutical ingredients. This modification often leads to enhanced metabolic stability, reducing the frequency of dosage required for patients.

Furthermore, in the agrochemical sector, this compound contributes to the synthesis of new pesticides with improved environmental profiles and efficacy. The fluorine content helps in resisting enzymatic degradation, ensuring longer-lasting protection for crops. Additionally, it serves as a fundamental raw material in the creation of new materials, where specific chemical resistance and thermal stability are required. Our fluorochemical platform supports diverse synthesis routes, catering to the evolving needs of chemists and engineers.

Quality Assurance and Supply

Shanghai Fluorine Technology is dedicated to establishing a complete fluorochemical products and technology platform. We provide customers with convenient one-stop services ranging from raw material procurement to final quality control. Our industrial chain covers fluorination technology research, product production, storage, and application support. We understand the critical nature of supply chain reliability in the chemical industry.

Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters. Our logistics network ensures safe and timely global delivery, adhering to all regulatory requirements for hazardous materials. We strive to build long-term partnerships based on trust, quality, and technical expertise.

Safety and Storage

Handling Difluoroacetic Acid requires strict adherence to safety protocols due to its corrosive nature. It should be stored in a dedicated corrosives area, away from incompatible substances such as strong bases and oxidizing agents. Personnel must wear appropriate personal protective equipment, including chemical-resistant gloves and eye protection, during handling. Proper ventilation is essential to prevent inhalation of vapors. In case of contact, immediate washing with plenty of water is recommended. We provide comprehensive safety data sheets to ensure safe usage in your facility.