Diisopropyl Azodicarboxylate
- CAS No.2446-83-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Diisopropyl Azodicarboxylate (DIAD) designed for advanced organic synthesis and pharmaceutical intermediate manufacturing.
Request Bulk PricingProduct Technical Details
Product Overview
Diisopropyl Azodicarboxylate, commonly abbreviated as DIAD, is a critical reagent in modern organic chemistry and pharmaceutical manufacturing. As the diisopropyl ester of azodicarboxylic acid, this compound serves as a versatile oxidizing agent and coupling partner in complex synthetic routes. Our facility produces this chemical under strict quality control protocols to ensure consistent performance in sensitive reactions. The material is characterized by its distinct orange-red transparent liquid appearance and high chemical stability when stored correctly.
We understand that reliability in raw materials is paramount for downstream synthesis. Therefore, every batch undergoes rigorous analytical testing to verify purity levels exceeding industry standards. This commitment to quality ensures that chemists and process engineers can rely on our product for reproducible results in laboratory and pilot-scale operations.
Key Specifications
| Items of Analysis | Standard of Analysis | Test Results |
|---|---|---|
| Appearance | Orange-red transparent liquid | Orange-red transparent liquid |
| Assay (GC) | ≥99% | 99.26% |
| Boiling Point | 75-77°C (0.25mmHg) | Conforms |
| Water Content | ≤0.1% | 0.03% |
| Identification | GC: Consistent with standard | Conforms |
| Conclusion | Conforms to Factory Standard | |
Industrial Applications
The primary application of Diisopropyl Azodicarboxylate lies in the Mitsunobu reaction, where it functions as an essential oxidizer for triphenylphosphine. This reaction mechanism is fundamental in the formation of ester, ether, and amine bonds, making DIAD indispensable in the synthesis of complex pharmaceutical intermediates and fine chemicals. Beyond the Mitsunobu protocol, this reagent is utilized in generating aza-Baylis-Hillman adducts with acrylates, expanding its utility in medicinal chemistry research.
Additionally, DIAD serves as a selective deprotectant for N-benzyl groups, offering chemists precise control over protecting group strategies during multi-step synthesis. Its high reactivity and selectivity make it a preferred choice for developing efficient manufacturing processes for advanced organic compounds. Whether used in process development or large-scale production, our DIAD supports the creation of high-value chemical entities.
Quality Assurance and Benefits
- High Purity Guarantee: Assay levels consistently above 99% to minimize side reactions.
- Low Water Content: Strictly controlled below 0.1% to prevent hydrolysis during storage.
- Reliable Supply Chain: Global manufacturer capable of meeting bulk demand schedules.
- Comprehensive Documentation: Full COA and technical support provided with every shipment.
Storage and Handling
Safety and stability are critical when handling reactive chemical reagents. Diisopropyl Azodicarboxylate should be stored in a cool, ventilated warehouse away from direct sources of fire and heat. The ambient temperature must not exceed 37 degrees Celsius to maintain chemical integrity. Proper packaging in 25 kg barrels ensures safe transport, though custom packaging solutions are available to meet specific logistical requirements. Always adhere to local safety regulations and consult the safety data sheet before use.
