Intermediates

Dimethyl (2-oxo-4-phenylbutyl)phosphonate

  • CAS No.41162-19-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of prostaglandin analogs like Bimatoprost and Latanoprost. Available in bulk quantities with comprehensive COA.

Request Bulk Pricing

Product Technical Details

Product Overview

Dimethyl (2-oxo-4-phenylbutyl)phosphonate is a specialized organophosphorus compound that serves as a critical building block in modern medicinal chemistry. Designed for high-efficiency synthetic routes, this phosphonate derivative offers exceptional stability and reactivity, making it an ideal candidate for the construction of complex pharmaceutical architectures. Our manufacturing process ensures consistent quality, catering specifically to the rigorous demands of the global pharmaceutical industry.

This compound is characterized by its distinct light yellow liquid appearance and robust chemical profile. It is engineered to facilitate the synthesis of advanced therapeutic agents, particularly within the realm of ocular pharmaceuticals. By providing a reliable source of this key intermediate, we support the development of life-improving medications that address critical health conditions.

Technical Specifications

Quality and precision are paramount in chemical manufacturing. The following table outlines the key physical and chemical properties of Dimethyl (2-oxo-4-phenylbutyl)phosphonate, verified through strict analytical protocols.

ParameterValue
CAS Number41162-19-0
Molecular FormulaC12H17O4P
Molecular Weight256.235 g/mol
AppearanceLight yellow liquid
Assay (Purity)≥85.0%
Density1.2±0.1 g/cm3
Boiling Point362.7±25.0 °C at 760 mmHg
Melting Point120-122 °C (0.5 mmHg)
Flash Point186.8±43.5 °C
Refractive Index1.494

Industrial Applications

The primary application of this phosphonate intermediate lies in the synthesis of prostaglandin analogs. It acts as a pivotal precursor in the manufacturing processes of well-known pharmaceutical agents such as Bimatoprost and Latanoprost. These final products are essential in the treatment of glaucoma and ocular hypertension, highlighting the significant medical value of this chemical building block.

Beyond specific API synthesis, this compound is utilized in various organic synthesis pathways where phosphonate chemistry is required. Its structural properties allow for versatile functionalization, enabling chemists to develop novel derivatives for research and development purposes. The high purity level ensures minimal byproduct formation during downstream reactions, optimizing overall yield and reducing purification costs.

Quality Assurance and Supply Chain

As a global manufacturer, we adhere to stringent quality control standards to ensure every batch meets international specifications. Each shipment is accompanied by a Certificate of Analysis (COA), providing full transparency regarding purity and physical properties. Our facility employs advanced analytical instrumentation to verify compliance with stated parameters.

  • Consistent batch-to-batch reproducibility for reliable manufacturing.
  • Flexible packaging options, including 200 kg drums or custom requirements.
  • Secure storage and logistics to maintain product integrity during transit.
  • Dedicated technical support for synthesis route optimization.

We recommend storing this product in a cool, ventilated place to maintain its stability over time. Our supply chain is optimized for global delivery, ensuring that research laboratories and production facilities receive their materials promptly. For bulk pricing and custom synthesis inquiries, our sales team is available to provide tailored solutions that meet your specific project needs.