Intermediates

Dimethyl (3,3-difluoro-2-oxoheptyl)phosphonate

  • CAS No.50889-46-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Dimethyl (3,3-difluoro-2-oxoheptyl)phosphonate (CAS 50889-46-8) is a specialized fluorinated phosphonate intermediate designed for advanced pharmaceutical synthesis and research applications.

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Product Technical Details

Product Overview

Dimethyl (3,3-difluoro-2-oxoheptyl)phosphonate represents a critical class of fluorinated organophosphorus compounds utilized extensively in modern medicinal chemistry. As a specialized building block, this chemical entity plays a pivotal role in the construction of complex pharmaceutical architectures, particularly within the synthesis chain of therapeutic agents targeting gastrointestinal disorders. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream processing.

The incorporation of fluorine atoms into organic molecules often enhances metabolic stability and bioavailability, making this phosphonate derivative highly valuable for drug discovery teams. We understand the precise requirements of process chemistry and deliver material that meets rigorous specifications for research and development purposes.

Technical Specifications

Our manufacturing process ensures that every batch of Dimethyl (3,3-difluoro-2-oxoheptyl)phosphonate adheres to high purity standards suitable for sensitive synthetic routes. The physical properties are carefully monitored to guarantee performance in reaction conditions.

ParameterValue
CAS Number50889-46-8
Molecular FormulaC9H17F2O4P
Molecular Weight258.199
AppearanceYellow liquid
Assay≥98.0%
Density1.162 g/cm³
Boiling Point301ºC
Flash Point135.8ºC
Refractive Index1.405

Industrial Applications

This fluorinated phosphonate serves primarily as a key intermediate in the multi-step synthesis of specific pharmaceutical compounds. It is notably utilized in the production pathway of Lubiprostone, highlighting its importance in the development of chloride channel activators. Chemists leverage the reactivity of the phosphonate group and the stability provided by the difluoro motif to construct target molecules with high precision.

  • Pharmaceutical intermediate synthesis
  • Organic fluorine chemistry research
  • Process development for therapeutic agents
  • Custom synthesis projects requiring phosphonate building blocks

Quality Assurance and Supply

We are committed to providing global partners with reliable supply chains and comprehensive documentation. Each shipment is accompanied by a Certificate of Analysis (COA) verifying the identity and purity of the material. Our quality management system ensures traceability from raw material sourcing to final packaging.

Packing options include 200 kg drums or customized containers based on client requirements. We recommend storing this product in a cool, ventilated area away from incompatible substances to maintain its integrity over time. For bulk inquiries or technical support regarding synthesis routes, our team is available to assist with competitive pricing and logistical solutions.