Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
- CAS No.61260-15-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate (CAS 61260-15-9), a key pharmaceutical intermediate in the synthesis of advanced oncology therapeutics such as Olaparib.
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Product Overview
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate, also known as 3-dimethoxyphosphoryl-3H-2-benzofuran-1-one, is a high-value organic phosphonate compound widely utilized as a critical building block in modern medicinal chemistry. With the CAS registry number 61260-15-9 and molecular formula C10H11O5P, this compound serves as an essential intermediate in the multi-step synthesis of targeted cancer therapeutics, particularly PARP inhibitors like Olaparib. Its well-defined reactivity profile and structural specificity make it indispensable in complex pharmaceutical API development pathways.
Specifications
| Molecular Formula | C10H11O5P |
|---|---|
| Molecular Weight | 242.17 g/mol |
| Appearance | White crystal |
| Purity | ≥98.0% |
| Packaging | 25 kg/drum; custom packaging available upon request |
| Storage | Store in a cool, dry, and well-ventilated area away from incompatible materials |
Industrial Applications
This phosphonate derivative is exclusively employed as a synthetic intermediate in regulated pharmaceutical manufacturing environments. Its primary application lies in the construction of heterocyclic scaffolds required for next-generation oncology drugs. Due to its role in patented therapeutic syntheses, distribution is restricted in jurisdictions where relevant intellectual property protections are active. As a non-formulation-ready chemical, it is not intended for direct use in consumer products, cosmetics, or nutraceuticals.
- High chemical stability under standard handling conditions
- Consistent batch-to-batch quality suitable for GMP-aligned processes
- Compliant with international regulatory standards for pharmaceutical intermediates
- Supplied with comprehensive documentation including Certificate of Analysis (COA)
Note: This product is offered strictly for research and industrial synthesis purposes under valid legal and regulatory frameworks. Export restrictions apply in patent-protected regions.
