Diphenyldiethoxysilane
- CAS No.2553-19-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity diphenyldiethoxysilane (CAS 2553-19-7) for use as a phenyl group transfer reagent in advanced organic synthesis and cross-coupling reactions.
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Product Overview
Diphenyldiethoxysilane is a high-value organosilicon intermediate widely employed in modern synthetic chemistry. With the molecular formula C₁₆H₂₀O₂Si and a molecular weight of 272.41 g/mol, this compound serves as a reliable source of phenyl groups in transition metal-catalyzed cross-coupling transformations. Its robust stability and controlled reactivity make it particularly suitable for pharmaceutical and fine chemical manufacturing processes requiring precise aryl incorporation.
Specifications
| Molecular Formula | C₁₆H₂₀O₂Si |
|---|---|
| Molecular Weight | 272.414 g/mol |
| Density | 1.033 g/cm³ |
| Boiling Point | 167°C |
| Flash Point | 175°C |
| Refractive Index | 1.525 |
| Appearance | Colorless or yellowish transparent liquid |
| Purity (GC) | ≥99.0% |
Industrial Applications
As a specialized silicon-based reagent, diphenyldiethoxysilane is primarily utilized in the cross-coupling of phenyl moieties under palladium or nickel catalysis. Key application areas include:
- Synthesis of biaryl scaffolds in active pharmaceutical ingredient (API) development
- Preparation of functionalized aromatic compounds for agrochemical intermediates
- Building block in materials science for tailored siloxane polymers
- Phenyl transfer agent in Hiyama-type coupling reactions
The compound’s high purity ensures minimal side reactions and consistent batch-to-batch performance in sensitive synthetic protocols.
Handling and Storage
Store in a cool, dry, and well-ventilated area away from moisture, heat sources, and incompatible materials. Supplied in 200 kg drums with custom packaging available upon request. Safety data sheets and certificates of analysis (COA) are provided with every shipment to support quality assurance in GMP-compliant environments.
