DL-Pantolactone

Product Overview

DL-Pantolactone, chemically known as 2-oxo-4,4-dimethyl-3-hydroxy-tetrahydrofuran, is a vital organic compound widely recognized in the pharmaceutical and nutraceutical industries. As a racemic mixture, this lactone serves as the fundamental building block for the synthesis of Pantothenic Acid, commonly known as Vitamin B5. Our manufacturing process ensures that every batch meets rigorous international standards, providing a reliable foundation for downstream chemical synthesis and formulation development.

In the global supply chain of fine chemicals, DL-Pantolactone holds a strategic position due to its versatility and high reactivity. It is primarily utilized in the production of calcium pantothenate and dexpanthenol, which are essential ingredients in various health supplements, cosmetic formulations, and pharmaceutical preparations. Our facility employs advanced catalytic techniques to achieve superior purity levels, minimizing impurities that could affect subsequent reaction yields.

Technical Specifications

Physical Properties

Understanding the physicochemical characteristics of DL-Pantolactone is essential for safe handling and optimal processing. The compound typically presents as a white needle-like solid with a distinct molecular structure that facilitates easy hydrolysis. With a molecular formula of C6H10O3 and a molecular weight of 130.14 g/mol, it exhibits stable thermal properties suitable for various industrial conditions.

• Density: 1.165 g/cm3 at standard conditions
• Boiling Point: 224.6ºC at 760 mmHg
• Melting Point: 74-78 ºC (lit.)
• Flash Point: 99ºC

Industrial Applications

The primary application of DL-Pantolactone lies in its conversion to pantoic acid through enzymatic hydrolysis, often utilizing lactase hydrolase from sources such as Fusarium oxysporum. This transformation is a critical step in the commercial production of Vitamin B5. Beyond nutraceuticals, derivatives of this lactone are employed in the synthesis of specialized compounds like 3,5-dinitrobenzoyl-DL-pantolactone, which finds use in analytical chemistry and chiral resolution processes.

In the cosmetic industry, derivatives resulting from DL-Pantolactone are valued for their moisturizing and skin-conditioning properties. Manufacturers seeking to develop high-performance skincare products rely on the consistent quality of this intermediate to ensure the efficacy and stability of their final formulations. Our product supports both large-scale industrial synthesis and specialized laboratory research.

Quality Assurance and Storage

Quality is paramount in chemical manufacturing. Each production lot undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and other analytical methods to verify assay purity and physical constants. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with customer specifications.

For optimal preservation, DL-Pantolactone should be stored in a cool, dry environment away from direct sunlight and moisture. Containers must remain tightly closed when not in use to prevent hydrolysis or contamination. Proper storage conditions maintain the chemical integrity of the product, ensuring it performs consistently during your synthesis processes. We recommend adhering to standard safety protocols when handling this material to ensure workplace safety and environmental protection.