(E)-Guggulsterone
- CAS No.39025-24-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity (E)-Guggulsterone intermediate for nutraceutical and pharmaceutical research. Available in bulk with full documentation.
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Product Overview
Our organization specializes in the supply of high-quality phytochemical intermediates, with a specific focus on steroid-based compounds derived from natural sources. (E)-Guggulsterone is a prominent bioactive steroid isolated from the resinous gum of the Commiphora mukul plant, commonly known as the guggul tree. This compound represents a critical component in the development of advanced nutraceutical formulations and pharmaceutical research projects targeting metabolic health. As a leading manufacturer, we ensure that every batch undergoes rigorous testing to meet international standards for purity and consistency.
Chemical Characteristics
This molecule exists as one of two distinct stereoisomers, the other being the Z-isomer. The E-configuration is particularly valued for its specific biological activity profiles. Chemically, it is characterized as a pregna-diene-dione derivative. Our synthesis and extraction processes are optimized to maximize the yield of the E-isomer while minimizing impurities. The compound exhibits stable physical properties suitable for various downstream processing methods. We maintain strict control over the molecular integrity to ensure reliable performance in your specific applications.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 39025-24-6 |
| Molecular Formula | C21H28O2 |
| Molecular Weight | 312.446 |
| Appearance | White to off-white powder |
| Assay (HPLC) | ≥99.0% |
| Melting Point | 170-171.5°C |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Industrial Applications
Primarily, this substance serves as a key active ingredient in the nutraceutical industry, specifically within supplements designed to support lipid metabolism and cardiovascular health. Research indicates its role as an antagonist of the farnesoid X receptor, which has historically linked it to cholesterol management pathways. Beyond supplements, it is utilized in pharmaceutical research as a reference standard or lead compound for developing new therapeutic agents. Our clients utilize this material for formulation development, performance benchmarking, and clinical study preparations. We support both large-scale production needs and smaller research quantities.
Quality Assurance and Logistics
Quality is the cornerstone of our manufacturing philosophy. Each production lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing all critical quality attributes. We employ advanced analytical techniques including HPLC and mass spectrometry to verify identity and purity. Regarding logistics, we offer flexible packaging solutions, typically supplying in 25kg drums, though custom packaging is available upon request to suit specific supply chain requirements. Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated environment to maintain stability. Our global distribution network ensures timely delivery with full regulatory compliance documentation.
