Intermediates

Ethyl 2-(1-Imidazolyl)acetate

  • CAS No.17450-34-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Ethyl 2-(1-Imidazolyl)acetate (CAS 17450-34-9) designed for pharmaceutical synthesis. Ideal intermediate for Zoledronic acid production with ≥99% assay.

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Product Technical Details

Product Overview

Ethyl 2-(1-Imidazolyl)acetate represents a critical heterocyclic building block within the modern pharmaceutical manufacturing landscape. As a specialized organic intermediate, this compound features a stable imidazole ring structure esterified with an ethyl acetate group, providing unique reactivity profiles essential for complex molecular synthesis. Our facility produces this chemical under strict quality control protocols to ensure consistency across large-scale batches.

The compound is primarily valued in the medicinal chemistry sector for its role in constructing nitrogen-containing heterocycles. Its high stability and defined physicochemical properties make it a preferred choice for process chemists developing robust synthetic routes. We prioritize industrial purity standards to minimize downstream purification challenges during API production.

Technical Specifications

Our manufacturing process adheres to rigorous analytical standards to guarantee product reliability. Each batch undergoes comprehensive testing using advanced chromatography and spectroscopy methods. The following table outlines the key physical and chemical parameters associated with this grade:

ParameterSpecification
Chemical NameEthyl 2-(1-Imidazolyl)acetate
CAS Registry Number17450-34-9
Molecular FormulaC7H10N2O2
Molecular Weight154.17 g/mol
AppearanceWhite powder
Assay (Purity)≥99.0%
Moisture Content≤0.25%
Total Impurities≤0.30%
Density1.14 g/cm3
Boiling Point293°C at 760 mmHg
Flash Point131°C
Refractive Index1.524

Industrial Applications

This intermediate serves as a vital precursor in the synthesis of various therapeutic agents. Notably, it is utilized in the manufacturing pathway of Zoledronic acid, a prominent bisphosphonate used in bone metabolism disorders. The integrity of the imidazole moiety in this ester is crucial for the subsequent cyclization and functionalization steps required to achieve the final active pharmaceutical ingredient.

Beyond specific API synthesis, Ethyl 2-(1-Imidazolyl)acetate is applicable in broader organic synthesis contexts where imidazole derivatives are required. Researchers utilize this building block for developing novel ligands, catalysts, and functional materials. Our supply chain supports both pilot-scale research and commercial production volumes, ensuring seamless scalability for our partners.

Quality Assurance And Handling

We maintain a certified quality management system to oversee every stage of production, from raw material sourcing to final packaging. A Certificate of Analysis (COA) accompanies every shipment, providing full transparency on test results. Our logistics team ensures that products are packed in secure 25kg cardboard drums or customized containers based on client requirements.

Proper storage is essential to maintain chemical stability. We recommend storing this material in a cool, dry, and well-closed container away from direct moisture and strong light or heat sources. By following these guidelines, users can preserve the specified purity and physical characteristics throughout the product shelf life. Contact our technical sales team for detailed safety data sheets and bulk pricing information.