Ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate
- CAS No.2199-51-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate (CAS 2199-51-1) serves as a critical pharmaceutical intermediate for kinase inhibitor synthesis, available in bulk quantities with full COA.
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Product Overview
Ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate is a specialized organic compound widely recognized for its pivotal role in the synthesis of advanced pharmaceutical agents. As a key building block in medicinal chemistry, this pyrrole derivative exhibits exceptional stability and reactivity, making it an indispensable precursor for the production of kinase inhibitors such as Sunitinib. Our manufacturing facility adheres to strict quality control protocols to ensure every batch meets the rigorous demands of the global pharmaceutical supply chain.
We understand that consistency in chemical structure and purity is paramount for downstream synthesis efficiency. Therefore, our production process utilizes refined synthetic routes designed to minimize impurities and maximize yield. This compound is characterized by its distinct red to brown powder appearance and robust physicochemical properties, ensuring reliable performance during complex organic transformations.
Technical Specifications
To guarantee compliance with international pharmaceutical standards, each lot undergoes comprehensive analytical testing. The following table outlines the critical quality attributes associated with this product:
| Parameter | Specification |
|---|---|
| CAS Number | 2199-51-1 |
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.21 g/mol |
| Appearance | Red to Brown Powder |
| Purity (HPLC) | ≥99.0% |
| Loss on Drying | ≤0.1% |
| Inorganic Salt | ≤0.1% |
| Heavy Metals | ≤10 ppm |
| Water Content | ≤0.1% |
Industrial Applications
The primary application of Ethyl 2,4-dimethyl-1H-pyrrole-3-carboxylate lies within the pharmaceutical sector, specifically as an intermediate in the manufacturing of anticancer therapeutics. It serves as a crucial structural component in the synthesis of Sunitinib Malate, a multi-targeted receptor tyrosine kinase inhibitor. The high purity levels we maintain are essential to prevent side reactions during the multi-step synthesis process, thereby ensuring the safety and efficacy of the final active pharmaceutical ingredient (API).
Beyond oncology, this pyrrole ester finds utility in research and development settings where novel heterocyclic compounds are explored. Chemists value this material for its predictable reactivity profile, which facilitates the construction of complex molecular architectures required for next-generation drug discovery programs.
Storage and Handling
Proper storage is critical to maintaining the integrity of this chemical intermediate. The product should be kept in a cool, dry environment with temperatures maintained between 2-8°C. Containers must be tightly sealed to prevent exposure to moisture, strong light, or heat sources, which could degrade the material over time. We recommend storing the compound in its original packaging until ready for use.
For logistics, we offer flexible packing options including 25kg cardboard drums or customized solutions based on specific customer requirements. Our global distribution network ensures timely delivery while maintaining cold chain conditions where necessary. Every shipment is accompanied by a Certificate of Analysis (COA) and relevant safety documentation to support regulatory compliance and quality assurance audits.
