Ethyl 2-Chloroacetoacetate
- CAS No.609-15-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Ethyl 2-Chloroacetoacetate (CAS 609-15-4) supplied for pharmaceutical synthesis. Ideal intermediate for Febuxostat production with ≥98.0% assay guarantee.
Request Bulk PricingProduct Technical Details
Product Overview
Ethyl 2-Chloroacetoacetate is a highly versatile organic building block extensively utilized in modern pharmaceutical and fine chemical synthesis. As a key chlorinated keto ester, it features significant reactivity due to the presence of both electrophilic carbonyl groups and a nucleophilic substitution site at the alpha position. This unique chemical structure makes it an indispensable precursor for constructing complex heterocyclic frameworks found in numerous therapeutic agents.
Our manufacturing facility produces this compound under strict quality control protocols to ensure consistent batch-to-batch reliability. We understand the critical nature of supply chain stability for downstream pharmaceutical manufacturers. Therefore, we prioritize high-efficiency synthesis routes that maximize yield while minimizing impurities, delivering a product that meets rigorous international standards for industrial application.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 609-15-4 |
| Molecular Formula | C6H9ClO3 |
| Molecular Weight | 164.587 g/mol |
| Appearance | Colorless clear liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 225.5±0.0 °C at 760 mmHg |
| Melting Point | -80 °C |
| Flash Point | 50.0±0.0 °C |
Industrial Applications
This chemical intermediate plays a pivotal role in the synthesis of advanced pharmaceutical compounds. It is particularly recognized as a crucial starting material in the production of Febuxostat, a non-purine selective inhibitor of xanthine oxidase used in the management of hyperuricemia and gout. The high reactivity of the chloroacetyl group facilitates efficient coupling reactions necessary for building the core structure of such medications.
Beyond pharmaceuticals, Ethyl 2-Chloroacetoacetate is employed in the development of agrochemicals and specialty polymers. Its ability to undergo cyclization and condensation reactions allows chemists to create diverse molecular architectures. We support research and development teams by providing material that enables precise reaction kinetics and reproducible outcomes in process scaling.
- Primary intermediate for gout medication synthesis
- Essential building block for heterocyclic chemistry
- Used in agrochemical active ingredient production
- Suitable for custom organic synthesis projects
Quality Assurance And Storage
Quality is the cornerstone of our operation. Every batch of Ethyl 2-Chloroacetoacetate undergoes comprehensive analytical testing using high-performance liquid chromatography and gas chromatography to verify purity levels. We provide a detailed Certificate of Analysis with every shipment, ensuring full transparency and compliance with your internal quality standards.
Proper storage is essential to maintain the stability of this compound. We recommend storing the product in a cool, ventilated area away from direct sunlight and moisture. Containers should remain tightly sealed when not in use to prevent hydrolysis. Our standard packaging consists of 200 kg drums, though we offer flexible packaging solutions tailored to specific logistical requirements. By choosing our global manufacturing services, you secure a reliable partner committed to safety, quality, and timely delivery for your chemical supply needs.
