Intermediates

Ethyl 2-Fluoropropionate

  • CAS No.349-43-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Ethyl 2-Fluoropropionate designed for advanced pharmaceutical and agrochemical synthesis workflows.

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Product Technical Details

Product Overview

Ethyl 2-Fluoropropionate, identified by CAS number 349-43-9, stands as a critical fluorinated building block within the realm of modern organic synthesis. As a specialized ester derivative, this compound introduces a strategic fluorine atom into molecular structures, significantly enhancing the metabolic stability and bioavailability of downstream pharmaceutical candidates. Our facility specializes in the production of high-grade fluorochemicals, ensuring that every batch meets rigorous international standards for purity and consistency.

The incorporation of fluorine into organic molecules is a cornerstone technique in medicinal chemistry and agrochemical development. This specific propionate ester serves as a versatile reagent for nucleophilic substitution reactions and esterification processes. By utilizing our premium grade material, research teams can achieve higher yields and cleaner reaction profiles, ultimately accelerating the timeline from laboratory discovery to commercial production.

Key Specifications

ParameterSpecification
Product NameEthyl 2-Fluoropropionate
CAS Number349-43-9
Molecular FormulaC5H9FO2
Molecular Weight120.12 g/mol
Purity>98.0% (GC)
Density0.997 g/cm3
Boiling Point125°C
Melting Point-29°C
Flash Point29°C
Refractive Index1.368

Industrial Applications

This fluorinated intermediate finds extensive utility across multiple high-value sectors. In the pharmaceutical industry, it is employed as a key synthon for developing novel therapeutic agents, particularly those requiring enhanced lipophilicity or resistance to enzymatic degradation. The unique electronic properties of the fluorine atom allow for fine-tuning of pKa values and binding affinities in drug-receptor interactions.

Beyond human health, this compound plays a vital role in the development of new pesticides and agricultural chemicals. The stability provided by the fluorine substitution helps active ingredients persist effectively in the field while maintaining safety profiles. Additionally, it serves as a precursor in the synthesis of advanced functional materials, including polymers and liquid crystals, where specific thermal and chemical resistance properties are required.

Quality Assurance and Supply Chain

Our company is committed to establishing a complete fluorochemical products and technology platform to provide customers with convenient one-stop services. We maintain a robust quality control system that includes comprehensive testing via Gas Chromatography (GC), Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS). Each shipment is accompanied by a detailed Certificate of Analysis (COA) to verify compliance with specified parameters.

  • Consistent batch-to-batch reproducibility for reliable R&D outcomes.
  • Secure packaging solutions to maintain stability during global transit.
  • Scalable production capacity to support both pilot studies and bulk manufacturing.
  • Dedicated technical support for synthesis route optimization and safety handling.

Shanghai Fluorine Technology strives to build a complete industrial chain from fluorine-containing raw material procurement to product application. We understand the critical nature of supply chain reliability in the chemical industry. Therefore, we maintain strategic stock levels and optimized logistics networks to ensure timely delivery to our global partners. Whether for academic research or industrial scale-up, our Ethyl 2-Fluoropropionate delivers the performance and purity required for demanding chemical transformations.