Ethyl 2-(2-Formamidothiazol-4-Yl)acetate
- CAS No.64987-05-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate essential for the synthesis of cephalosporin antibiotics like Ceftazidime. Available in bulk quantities with full quality documentation.
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Product Overview
Ethyl 2-(2-Formamidothiazol-4-Yl)acetate is a critical pharmaceutical intermediate widely recognized for its role in the production of advanced beta-lactam antibiotics. This specialized chemical compound serves as a foundational building block in the synthesis of life-saving medications, including Ceftazidime and Aztreonam. Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream pharmaceutical manufacturing processes.
As a key component in modern medicinal chemistry, this thiazole derivative exhibits excellent stability and reactivity profiles suitable for complex organic synthesis. We understand the stringent requirements of the pharmaceutical industry, which is why our production lines are optimized to deliver high-purity materials that meet international standards for active pharmaceutical ingredient (API) synthesis.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 64987-05-9 |
| Molecular Formula | C8H10N2O3S |
| Molecular Weight | 214.24 g/mol |
| Appearance | Off-white to pale yellow powder |
| Purity | ≥98.0% |
| Melting Point | 130-132°C |
| Density | 1.354 g/cm3 |
| Refractive Index | 1.586 |
Industrial Applications
The primary application of Ethyl 2-(2-Formamidothiazol-4-Yl)acetate lies within the pharmaceutical sector, specifically in the manufacturing of third-generation cephalosporins. It acts as a vital side-chain intermediate for Ceftazidime, a potent antibiotic used to treat a wide range of bacterial infections. Additionally, it is utilized in the synthesis of Aztreonam, a monobactam antibiotic essential for patients with specific beta-lactam allergies.
Beyond antibiotic synthesis, this compound is valuable in research and development settings focused on novel thiazole-based therapeutics. Its chemical structure allows for versatile functionalization, making it a preferred choice for chemists developing new antimicrobial agents. Our customers rely on this material for scale-up processes where batch-to-batch consistency is paramount.
Quality Assurance and Advantages
We prioritize quality assurance through rigorous testing at every stage of production. Each batch undergoes comprehensive analysis using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) to verify purity and structural integrity. Choosing our product offers several distinct advantages for your supply chain:
- Consistent high purity levels exceeding 98 percent for optimal reaction yields.
- Full traceability with detailed Certificate of Analysis (COA) provided for every shipment.
- Scalable production capacity to meet both pilot-scale and commercial manufacturing demands.
- Strict adherence to safety and environmental regulations during manufacturing.
- Dedicated technical support team available to assist with synthesis optimization.
Packaging and Storage
To maintain product integrity during transit, Ethyl 2-(2-Formamidothiazol-4-Yl)acetate is packaged in secure 25 kg drums lined with moisture-resistant materials. Custom packaging solutions are available upon request to accommodate specific logistical requirements. For storage, we recommend keeping the material in a cool, well-ventilated area away from direct sunlight and sources of ignition. Proper storage ensures the chemical stability and longevity of the product until it is ready for use in your synthesis processes.
