Intermediates

Ethyl 3-Amino-4,4,4-Trifluorocrotonate

  • CAS No.372-29-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity fluorinated building block essential for pharmaceutical and agrochemical synthesis, available in bulk quantities with full quality documentation.

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Product Technical Details

Product Overview

Ethyl 3-Amino-4,4,4-Trifluorocrotonate is a highly specialized fluorinated organic intermediate designed for advanced chemical synthesis. As a key building block in modern medicinal chemistry, this compound features a stable trifluoromethyl group that enhances the metabolic stability and bioavailability of final active pharmaceutical ingredients. Our facility produces this material under strict quality control standards to ensure consistency for large-scale industrial applications.

The incorporation of fluorine atoms into organic molecules is a critical strategy in the development of new drugs and agrochemicals. This specific ester serves as a versatile precursor, allowing chemists to introduce trifluoromethyl functionality into complex molecular architectures. Whether used in the synthesis of heterocyclic compounds or as a reagent in condensation reactions, this product delivers reliable performance.

Technical Specifications

We maintain rigorous testing protocols for every batch to guarantee compliance with international standards. The following table outlines the key physical and chemical properties verified during our quality assurance process.

ParameterSpecification
CAS Number372-29-2
Molecular FormulaC6H8F3NO2
Molecular Weight183.13 g/mol
AppearanceLight yellow liquid or white crystal
Density1.245 g/mL at 25 °C
Boiling Point83 °C at 15 mm Hg
Refractive Indexn20/D 1.424
Purity>98.0% (GC)

Industrial Applications

This fluorinated intermediate is widely utilized across multiple high-value sectors. In the pharmaceutical industry, it acts as a crucial synthon for developing novel therapeutic agents, particularly those requiring enhanced lipophilicity. In agrochemical research, it supports the creation of next-generation pesticides with improved environmental profiles. Additionally, it finds application in the synthesis of advanced functional materials where fluorine content dictates performance characteristics.

  • Pharmaceutical API synthesis and drug discovery
  • Agrochemical and pesticide development
  • Fluorinated material science research
  • Organic synthesis building block

Quality Commitment and Supply

Our company is dedicated to establishing a comprehensive fluorochemical technology platform. We provide one-stop services ranging from raw material procurement to final product quality control. Every shipment is accompanied by a Certificate of Analysis (COA) to verify purity and identity. We support global logistics and offer flexible packaging options to meet the diverse needs of research laboratories and manufacturing plants. Partner with us for reliable supply chains and technical expertise in fluorine chemistry.