Ethyl 3-Chloro-4-Fluorobenzoate
- CAS No.137521-81-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Ethyl 3-Chloro-4-Fluorobenzoate (CAS 137521-81-4) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical applications.
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Product Overview
Ethyl 3-Chloro-4-Fluorobenzoate represents a critical component in the realm of advanced organic synthesis. As a fluorinated aromatic ester, this compound is engineered to meet the demanding requirements of modern pharmaceutical and agrochemical development. The strategic placement of chlorine and fluorine atoms on the benzene ring provides distinct electronic effects that enhance reactivity in various chemical transformations. Our commitment to excellence ensures that every batch delivers the high purity necessary for sensitive synthetic pathways.
In the context of medicinal chemistry, fluorinated intermediates are highly valued for their ability to improve metabolic stability and bioavailability in final drug products. This specific benzoate derivative serves as a robust building block for constructing complex heterocyclic systems. We understand the importance of supply chain reliability, which is why our production capabilities are scaled to support both research-scale quantities and bulk industrial demands. The consistency of our material allows chemists to reproduce results with confidence.
Technical Specifications
Transparency and precision define our quality control protocols. Each production run is subjected to comprehensive analytical verification using state-of-the-art instrumentation. The data below reflects the standard specifications for our commercial grade Ethyl 3-Chloro-4-Fluorobenzoate. Deviations are minimized through rigorous process monitoring.
| Parameter | Specification |
|---|---|
| CAS Registry Number | 137521-81-4 |
| Chemical Formula | C9H8ClFO2 |
| Molecular Weight | 202.61 g/mol |
| Physical Form | White Crystalline Solid |
| Purity (HPLC) | ≥99.0% |
| Melting Range | 38-41°C |
| Boiling Point | 255.4°C |
| Refractive Index | 1.506 |
| Moisture Level | ≤0.2% |
Industrial Applications
The primary application of this compound lies in its function as a versatile synthetic intermediate. It is extensively used in the preparation of quinolone antibiotics and other therapeutic classes where halogenated aromatic rings are essential. The fluoro substituent, in particular, offers unique advantages in modulating the lipophilicity and binding affinity of potential drug candidates. Additionally, this ester is utilized in the agrochemical sector for developing novel pesticides and herbicides.
Our material supports a wide range of chemical reactions, including ester hydrolysis, amidation, and cross-coupling methodologies. Chemists appreciate the low moisture content and high assay value, which reduce the need for extensive purification steps downstream. This efficiency translates to cost savings and faster time-to-market for new products. We collaborate closely with R and D teams to ensure our specifications align with their specific process requirements.
Quality Assurance and Logistics
Safety and compliance are the cornerstones of our operation. We maintain a robust quality management system that tracks every stage of production from raw material sourcing to final packaging. Every shipment is accompanied by a detailed Certificate of Analysis (COA) and safety data sheets. Our packaging options include standard 25 kg drums, with flexibility for custom configurations based on customer volume needs.
Proper storage is essential to maintain product integrity. We recommend storing Ethyl 3-Chloro-4-Fluorobenzoate in a cool, dry, and well-ventilated area, protected from direct sunlight and moisture. Our global distribution network ensures secure and timely delivery to facilities around the world. By choosing us as your partner, you gain access to technical support, competitive bulk pricing, and a reliable supply chain dedicated to your success.
