Ethyl 3-Cyclopropyl-3-Oxopropanoate
- CAS No.24922-02-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity Ethyl 3-Cyclopropyl-3-Oxopropanoate liquid designed for pharmaceutical synthesis. Ideal intermediate for Rosuvastatin Calcium production with consistent quality.
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Product Overview
Ethyl 3-Cyclopropyl-3-Oxopropanoate, identified by CAS number 24922-02-9, is a specialized organic compound widely utilized in the pharmaceutical industry. This versatile building block features a unique cyclopropyl ring structure combined with ketone and ester functional groups, making it highly reactive for various synthetic transformations. Our manufacturing process ensures exceptional purity levels, typically exceeding 95.0 percent, to meet the rigorous demands of modern drug synthesis.
As a critical precursor, this compound plays an indispensable role in the production of high-value therapeutic agents. Specifically, it serves as a key intermediate in the multi-step synthesis of Rosuvastatin Calcium, a prominent medication used for managing cholesterol levels. The stability and reactivity profile of this molecule allow chemists to efficiently construct complex molecular architectures required for advanced pharmaceutical formulations.
Chemical Properties and Specifications
Understanding the physical and chemical characteristics of this intermediate is essential for safe handling and effective utilization in synthesis pathways. The compound presents as a colorless to yellowish liquid under standard conditions, with distinct thermal properties that facilitate processing. Our quality control laboratories employ advanced analytical techniques, including HPLC and NMR spectroscopy, to verify every batch against strict specifications.
| Parameter | Specification |
|---|---|
| CAS Number | 24922-02-9 |
| Molecular Formula | C8H12O3 |
| Molecular Weight | 156.18 g/mol |
| Appearance | Colorless or yellowish liquid |
| Assay | Greater than or equal to 95.0 percent |
| Density | 1.135 g/cm3 |
| Boiling Point | 212.9 degrees Celsius |
| Flash Point | 84.6 degrees Celsius |
Industrial Applications
The primary application of Ethyl 3-Cyclopropyl-3-Oxopropanoate lies in the synthesis of statin pharmaceuticals. Its structural features enable specific condensation and alkylation reactions necessary for building the core scaffold of Rosuvastatin. Beyond this specific use, the compound is valuable in research and development settings where cyclopropyl-containing motifs are required for exploring new chemical entities.
- Pharmaceutical intermediate for cardiovascular medications
- Building block for complex organic synthesis
- Reagent for medicinal chemistry research
- Precursor for custom synthesis projects
- Component in scale-up production processes
Quality Assurance and Packaging
We maintain a robust quality management system to ensure product consistency and reliability. Each production batch undergoes comprehensive testing, and a Certificate of Analysis (COA) is provided with every shipment. This documentation includes detailed results for purity, identity, and physical properties, ensuring full transparency for our global partners.
For logistics, the product is securely packaged in 200 kg drums to maintain integrity during transit. Custom packaging solutions are available upon request to accommodate specific client requirements. Proper storage in a cool, ventilated area is recommended to preserve stability and prevent degradation over time. Our team offers technical support to assist with handling guidelines and safety data interpretation.
Safety and Handling
Safe handling practices are paramount when working with chemical intermediates. Users should employ appropriate personal protective equipment, including gloves and eye protection, during all operations. Adequate ventilation is necessary to manage vapors, and storage areas should be kept away from incompatible substances. By adhering to these guidelines, laboratories and production facilities can maintain a safe working environment while leveraging the chemical potential of this high-quality intermediate.
