Ethyl 5-bromobenzofuran-2-carboxylate
- CAS No.84102-69-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in the synthesis of therapeutic agents. Available in bulk with strict quality control and global shipping options.
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Product Overview
Ethyl 5-bromobenzofuran-2-carboxylate stands as a pivotal specialized building block within the realm of advanced organic synthesis and medicinal chemistry. This heterocyclic compound features a benzofuran core substituted with a bromo group and an ethyl ester functionality, making it highly versatile for various chemical transformations. Our facility produces this material under stringent quality management systems to ensure consistency and reliability for downstream pharmaceutical manufacturing processes.
The unique structural arrangement of this molecule allows chemists to utilize the bromo substituent for cross-coupling reactions, such as Suzuki or Heck couplings, while the ester group offers opportunities for hydrolysis, reduction, or amidation. This dual reactivity profile makes it an indispensable precursor in the construction of complex molecular architectures required for modern therapeutic development.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Ethyl 5-bromobenzofuran-2-carboxylate |
| CAS Number | 84102-69-2 |
| Molecular Formula | C11H9BrO3 |
| Molecular Weight | 269.091 g/mol |
| Appearance | Light yellow solid powder |
| Purity | ≥99.0% |
| Melting Point | 60-62°C |
| Boiling Point | 328.3°C at 760 mmHg |
| Density | 1.52 g/cm3 |
| Flash Point | 152.4°C |
Industrial Applications
This compound is primarily utilized as a key intermediate in the synthesis of specialized pharmaceutical agents. It serves as a critical starting material for the production of complex drug substances, including specific therapeutic compounds like Veratrazodone hydrochloride. The high purity grade we supply ensures minimal impurity carryover into final active pharmaceutical ingredients, thereby supporting regulatory compliance and patient safety.
Beyond pharmaceuticals, this benzofuran derivative finds utility in agrochemical research and material science where heterocyclic frameworks are required. Our R&D team continuously optimizes the synthesis route to maximize yield and minimize environmental impact, aligning with green chemistry principles.
Quality Assurance And Storage
Quality is the cornerstone of our manufacturing philosophy. Every batch of Ethyl 5-bromobenzofuran-2-carboxylate undergoes rigorous analytical testing using HPLC, NMR, and MS techniques to verify identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee transparency and traceability.
- Strict adherence to ISO quality management standards.
- Regular stability testing to ensure shelf-life integrity.
- Customized packaging solutions available upon request.
For optimal stability, the product should be stored in a cool and dry well-closed container. It is essential to keep the material away from moisture and strong light or heat sources. Refrigerated storage is recommended for long-term preservation to maintain physical and chemical properties. We offer flexible packing options, including 25kg cardboard drums, tailored to meet specific logistical requirements of our global clientele.
