Intermediates

Ethyl 5-Nitrobenzofuran-2-Carboxylate

  • CAS No.69404-00-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of Vilazodone. Available in bulk quantities with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

Ethyl 5-Nitrobenzofuran-2-Carboxylate is a specialized organic compound characterized by its nitrobenzofuran core structure. This chemical serves as a critical building block in the pharmaceutical industry, particularly within the synthesis of advanced therapeutic agents. Our manufacturing process ensures that each batch meets rigorous international standards for purity and consistency, making it an ideal choice for research and development laboratories as well as large-scale production facilities.

As a key intermediate, this compound facilitates the construction of complex molecular architectures required for modern medicinal chemistry. The presence of the nitro group and the ester functionality allows for versatile chemical transformations, enabling chemists to derive various downstream products efficiently. We are committed to supplying high-quality materials that support the development of innovative healthcare solutions.

Technical Specifications

ParameterValue
Chemical NameEthyl 5-Nitrobenzofuran-2-Carboxylate
CAS Number69404-00-8
Molecular FormulaC11H9NO5
Molecular Weight235.19 g/mol
Purity≥98%
AppearanceSolid
Melting Point150-155°C
Boiling Point359.698°C at 760 mmHg
Density1.363 g/cm3
Flash Point171.34°C

Industrial Applications

This compound is primarily utilized as a precursor in the synthesis of Vilazodone, a pharmaceutical agent used in the treatment of major depressive disorder. The high purity level of our product ensures minimal impurity carryover into the final active pharmaceutical ingredient, which is crucial for regulatory compliance and patient safety. Beyond this specific application, the chemical structure offers potential utility in the development of other benzofuran-based derivatives for neurological and psychiatric therapeutic areas.

Our clients leverage this intermediate for process optimization, scale-up studies, and generic drug development. The reliability of the supply chain allows pharmaceutical manufacturers to maintain consistent production schedules without interruption. We support our partners with technical data packages that facilitate smooth registration processes in various global markets.

Quality Assurance and Storage

Quality is the cornerstone of our operation. Every batch of Ethyl 5-Nitrobenzofuran-2-Carboxylate undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and transparency. Our facilities adhere to strict safety and environmental protocols to maintain product integrity.

Proper storage is essential to maintain the stability of this chemical. It should be kept in a cool, dry, and well-ventilated area, away from direct sunlight and moisture. Containers must be tightly closed when not in use to prevent degradation. We recommend storage in a refrigerator for long-term preservation. Packaging is available in 25kg cardboard drums or customized according to specific customer requirements to ensure safe transport globally.