Ethyl 5-(trifluoromethoxy)indole-2-carboxylate
- CAS No.175203-82-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Ethyl 5-(trifluoromethoxy)indole-2-carboxylate (CAS 175203-82-4) designed for advanced organic synthesis and pharmaceutical research applications.
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Product Overview
Ethyl 5-(trifluoromethoxy)indole-2-carboxylate is a specialized fluorinated indole derivative engineered for high-performance organic synthesis. As a critical building block in medicinal chemistry, this compound features a stable trifluoromethoxy group that enhances metabolic stability and lipophilicity in downstream pharmaceutical candidates. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal choice for research and development teams focused on novel therapeutic discovery.
We adhere to strict quality control protocols to guarantee the integrity of every molecule. This intermediate is widely utilized in the construction of complex heterocyclic systems, serving as a foundational element for kinase inhibitors, serotonin modulators, and other bioactive agents. By selecting our premium grade material, laboratories can accelerate their synthesis timelines while maintaining rigorous scientific standards.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 175203-82-4 |
| Molecular Formula | C12H10F3NO3 |
| Molecular Weight | 273.21 g/mol |
| Appearance | Brown powder |
| Assay (Purity) | ≥97.0% |
| Melting Point | 144 °C |
| Boiling Point | 339.9 °C at 760 mmHg |
| Density | 1.389 g/cm3 |
| Flash Point | 159.4 °C |
Industrial Applications
This fluorinated indole ester is primarily employed as a versatile intermediate in the pharmaceutical and agrochemical sectors. Its unique structural properties allow for diverse functionalization strategies, facilitating the creation of targeted drug molecules. Common applications include:
- Synthesis of novel indole-based pharmaceutical APIs.
- Development of chemical probes for biological research.
- Construction of complex heterocyclic scaffolds.
- Use in structure-activity relationship (SAR) studies.
Our global supply chain ensures timely delivery to research institutions and manufacturing facilities worldwide. We support various scales of production, from gram-level research quantities to multi-kilogram commercial batches, accommodating the diverse needs of our partners.
Quality Assurance and Storage
Every shipment of Ethyl 5-(trifluoromethoxy)indole-2-carboxylate is accompanied by a comprehensive Certificate of Analysis (COA), detailing purity levels and physical characteristics. We recommend storing this material in a cool, ventilated environment away from direct sunlight and moisture to maintain optimal stability. Proper handling procedures should be followed in accordance with standard laboratory safety guidelines. For custom packaging requirements or technical support regarding synthesis routes, our expert team is available to assist with your specific project needs.
