Intermediates

Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate

  • CAS No.6836-21-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate (CAS 6836-21-1) serves as a critical pharmaceutical intermediate for Agomelatine synthesis.

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Product Technical Details

Product Overview

Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate, universally recognized by its CAS registry number 6836-21-1, stands as a sophisticated organic compound essential within the modern pharmaceutical synthesis landscape. This naphthalene derivative serves as a critical building block, specifically engineered for researchers and manufacturers engaged in the production of advanced therapeutic agents. Our facility specializes in the large-scale production of this high-value intermediate, ensuring consistent quality and reliable supply chains for global partners who demand excellence in chemical raw materials.

The chemical structure features a methoxy-substituted naphthalene ring coupled with an acetate ester group, providing unique reactivity profiles suitable for complex organic transformations. As a key precursor, it plays a pivotal role in constructing the molecular framework required for specific neurological therapeutics. We understand the stringent demands of the pharmaceutical industry, which is why our manufacturing processes adhere to rigorous quality management systems and environmental safety standards. Our commitment to excellence ensures that every molecule meets the highest specifications for purity and performance.

Technical Specifications

PropertySpecification
CAS Number6836-21-1
Molecular FormulaC15H16O3
Molecular Weight244.29 g/mol
AppearanceColorless or light yellow transparent liquid or solid
Purity≥98.0%
Density1.126 g/cm3
Boiling Point370.4°C at 760 mmHg
Flash Point155.1°C
Refractive Index1.572

Industrial Applications

The primary application of Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate lies in its function as a specialized intermediate for the synthesis of Agomelatine. Agomelatine is a well-known pharmaceutical agent used in the management of depressive disorders, acting as a melatonin receptor agonist and serotonin antagonist. The precision required in synthesizing such active pharmaceutical ingredients (APIs) demands intermediates of exceptional purity and structural integrity. Any impurity at this stage can propagate through the synthesis chain, affecting the final drug product's safety and efficacy.

Our product facilitates efficient synthetic routes, reducing waste and improving overall yield in downstream processing. Chemical engineers and process chemists value this compound for its stability and predictable reaction kinetics. Whether utilized in laboratory-scale research or industrial-scale manufacturing, this intermediate supports the development of safe and effective medicinal products. We work closely with clients to optimize usage rates and provide technical support for integration into existing production lines.

Quality Assurance and Storage

Quality is the cornerstone of our operation. Every batch of Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate undergoes comprehensive analytical testing, including High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), and mass spectrometry, to verify identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full transparency and compliance with international standards. Our quality control team operates independently to guarantee unbiased results.

Proper storage is essential to maintain product stability over time. The material should be kept in tightly closed containers within a cool, dry, and well-ventilated area. It is crucial to protect the substance from moisture and incompatible materials such as strong oxidizing agents. We recommend standard safety protocols during handling, including the use of appropriate personal protective equipment like gloves and safety goggles. Our packaging options include 25kg cardboard drums or custom solutions tailored to specific logistical requirements, ensuring safe transport across borders.