Intermediates

Ethyl Bromopyruvate

  • CAS No.70-23-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Ethyl bromopyruvate liquid for advanced heterocyclic synthesis. Reliable supply with full documentation.

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Product Technical Details

Product Overview

Ethyl bromopyruvate is a highly versatile organic intermediate characterized by its alpha-halo ketone ester structure. This chemical compound serves as a critical building block in the field of advanced organic synthesis, particularly valued for its reactivity in forming complex heterocyclic systems. Our facility produces this reagent under strict quality control protocols to ensure consistent performance in research and industrial applications. As a leading global manufacturer, we prioritize purity and stability to support demanding synthetic routes.

The compound is recognized for its utility in medicinal chemistry and material science development. It functions effectively as an alkylating agent and a precursor for various pharmacologically active scaffolds. Researchers rely on its specific reactivity profile to construct nitrogen and sulfur-containing rings efficiently. Our production process emphasizes minimal impurity profiles to prevent side reactions during downstream processing.

Technical Specifications

ParameterSpecification
CAS Number70-23-5
Molecular FormulaC5H7BrO3
Molecular Weight195.01 g/mol
AppearanceWhite to light yellow liquid
Density1.554 g/mL at 25 °C
Boiling Point98-100 °C at 10 mm Hg
Refractive Indexn20/D 1.469
Flash Point210 °F
Storage Temperature2-8 °C

Applications and Usage

This intermediate is primarily employed in heterocyclic ring-closing reactions. It is instrumental in the synthesis of thiazoles, imidazoles, and other nitrogenous heterocycles found in modern pharmaceutical candidates. The bromine atom provides a suitable leaving group for nucleophilic substitution, while the keto ester moiety allows for further functionalization. This dual reactivity makes it indispensable for multi-step synthesis pathways.

  • Facilitates efficient construction of five-membered heterocyclic rings.
  • Used in the development of novel enzyme inhibitors for research purposes.
  • Supports the creation of specialized ligands for coordination chemistry.
  • Applicable in material science for creating functionalized polymers.

Quality Assurance and Handling

We maintain rigorous quality assurance standards throughout the manufacturing process. Each batch undergoes comprehensive analysis using GC and HPLC methods to verify purity levels. A Certificate of Analysis (COA) is provided with every shipment to ensure transparency and compliance with international standards. Proper handling is essential due to the chemical nature of this substance.

Users should operate within a well-ventilated environment and wear appropriate personal protective equipment including gloves and safety goggles. Storage at recommended temperatures between 2-8 °C is crucial to maintain stability and prevent degradation over time. Our logistics team ensures secure packaging to prevent leakage during global transit. For large-scale requirements, we offer flexible bulk pricing and dedicated technical support to optimize your synthesis protocols.