Ethyl (Ethoxymethylene)cyanoacetate
- CAS No.94-05-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Ethyl (ethoxymethylene)cyanoacetate (CAS 94-05-3), a key building block for pharmaceutical, agrochemical, and dye synthesis.
Request Bulk PricingProduct Technical Details
Product Overview
Ethyl (ethoxymethylene)cyanoacetate is a versatile organic intermediate widely employed in the synthesis of active pharmaceutical ingredients (APIs), pesticides, and specialty dyes. With a molecular formula of C8H11NO3 and a molecular weight of 169.18 g/mol, this compound features a reactive enone structure combined with cyano and ester functionalities, making it highly valuable in multicomponent condensation reactions and heterocyclic ring formations.
Specifications
| Appearance | Off-white to light yellow solid |
|---|---|
| Assay (Purity) | ≥98.0% (Typical: 98.91%) |
| Melting Point | 48.5–51.5 °C (Typical: 50.7–50.8 °C) |
| Residue on Ignition | ≤0.5% |
| Loss on Drying | ≤0.5% |
| Density | 1.075 g/cm³ |
| Boiling Point | 190–191 °C at 30 mmHg |
| Refractive Index | 1.452 |
| Flash Point | >230 °F |
Industrial Applications
As a critical synthon in fine chemical manufacturing, Ethyl (ethoxymethylene)cyanoacetate serves as a precursor in the construction of pyridine, pyrimidine, and other nitrogen-containing heterocycles. Its primary applications include:
- Pharmaceutical intermediates for antihypertensive, anti-inflammatory, and antimicrobial agents
- Agrochemical intermediates in the development of selective herbicides and insecticides
- Dye and pigment synthesis requiring electron-deficient olefinic structures
Due to its high reactivity and selectivity, it is favored in scalable, cost-efficient synthetic routes under mild reaction conditions.
Handling and Storage
Store in a tightly sealed container in a cool, dry, and well-ventilated area away from heat, sparks, open flames, and incompatible materials such as strong oxidizers or bases. Keep in a designated corrosives storage zone. Standard industrial hygiene practices are recommended during handling.
Packaging
Supplied in 25 kg fiber drums with inner polyethylene liners. Custom packaging options are available upon request to meet specific logistical or regulatory requirements.
