Ethyl (R)-(+)-4-Chloro-3-Hydroxybutyrate
- CAS No.90866-33-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity chiral intermediate essential for L-carnitine synthesis, offering superior enantiomeric excess and reliable supply for pharmaceutical manufacturing.
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Product Overview
Ethyl (R)-(+)-4-Chloro-3-Hydroxybutyrate represents a critical chiral building block within the pharmaceutical and nutraceutical supply chain. As a key precursor, this compound is meticulously synthesized to ensure high stereochemical purity, which is paramount for downstream applications. Our manufacturing facility adheres to strict international standards, delivering a product that meets the rigorous demands of modern organic synthesis. The unique structural configuration allows for efficient conversion into high-value end products, making it a preferred choice for process chemists and procurement managers alike.
The chemical stability and reactivity of this butyrate ester are optimized for large-scale production environments. We understand that consistency is key in industrial chemistry. Therefore, every batch undergoes comprehensive analysis to verify physical constants such as density, boiling point, and refractive index. These parameters are not merely theoretical; they serve as practical indicators of purity and usability in complex reaction sequences. By maintaining tight control over these variables, we minimize variability in our clients' production lines.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Ethyl (R)-(+)-4-Chloro-3-Hydroxybutyrate |
| CAS Number | 90866-33-4 |
| Molecular Formula | C6H11ClO3 |
| Molecular Weight | 166.603 |
| Appearance | Colorless to light yellow transparent liquid |
| Assay | ≥96.0% |
| Enantiomeric Excess (EE) | ≥99.0% |
| Boiling Point | 93-95°C (5mmHg) |
| Density | 1.2±0.1 g/cm3 |
Industrial Applications
Primary utilization focuses on the synthesis of L-carnitine, a vital compound in metabolic health applications. The high enantiomeric excess provided by our grade ensures that the final biological activity meets therapeutic expectations. Beyond this primary application, the compound serves as a versatile intermediate for various fine chemical transformations. Researchers value its reliability when developing new synthetic routes or scaling up existing protocols. The compatibility with standard reduction and substitution reactions enhances its utility across multiple sectors.
The versatility of this chloro-hydroxy ester extends into specialized organic synthesis where chiral centers must be preserved. It is an ideal candidate for processes requiring high optical purity to avoid costly separation steps later in the synthesis tree. By starting with a high-quality intermediate, manufacturers can reduce waste and improve overall yield. This efficiency translates to cost savings and a reduced environmental footprint, aligning with green chemistry principles.
Quality Assurance And Control
Quality is the cornerstone of our operation. We employ advanced chromatographic techniques to quantify enantiomeric excess, ensuring levels exceed 99 percent. The assay value is consistently maintained above 96 percent, guaranteeing minimal impurity profiles. Our quality assurance team issues a Certificate of Analysis with every shipment, providing full transparency. This commitment to data integrity builds long-term partnerships with global manufacturers who require dependable raw materials for their regulated products.
In addition to standard chemical testing, we perform rigorous stability studies under various conditions. This data supports our clients in defining their own storage protocols and shelf-life expectations. The low vapor pressure at ambient temperatures reduces handling risks, contributing to a safer workplace environment. Our technical support team is available to assist with method validation or troubleshooting, ensuring that the material performs as expected in your specific process setup.
Packaging And Storage
Logistics are handled with precision to preserve product integrity. Standard packaging involves 200 kg drums, though custom solutions are available to suit specific volume requirements. Storage recommendations emphasize cool and ventilated conditions to prevent degradation. Our supply chain team coordinates global shipping to ensure timely delivery while complying with all hazardous material regulations. This end-to-end support simplifies procurement and allows our clients to focus on their core research and development activities.
