Intermediates

Ethyl Trifluoroacetate

  • CAS No.383-63-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Ethyl Trifluoroacetate for pharmaceutical synthesis. Reliable supply with COA and competitive bulk pricing for global manufacturers.

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Product Technical Details

Product Overview

Ethyl Trifluoroacetate is a vital fluorinated organic compound widely utilized in the pharmaceutical and agrochemical industries. As a key ester derivative of trifluoroacetic acid, it serves as an essential building block for introducing trifluoromethyl groups into complex molecular structures. The presence of fluorine atoms often enhances the biological activity and metabolic stability of the final drug product. Our facility produces this reagent with stringent quality controls to ensure consistent performance in sensitive synthetic pathways. The compound is characterized by its high reactivity and stability, making it a preferred choice for professional laboratory and industrial-scale applications. We are committed to supplying high-grade chemical intermediates that meet the rigorous demands of modern medicinal chemistry.

Technical Specifications

We adhere to international standards for chemical purity and safety. Each batch undergoes rigorous gas chromatography analysis to verify composition and impurity profiles. The following table outlines the typical physical and chemical properties of our premium grade Ethyl Trifluoroacetate. These parameters are critical for process engineers when designing reaction conditions and safety protocols.

Parameter Value
CAS Number 383-63-1
Molecular Formula C4H5F3O2
Molecular Weight 142.077 g/mol
Appearance Colorless Transparent Liquid
Purity (GC) ≥98.0%
Boiling Point 61.5±3.0 °C at 760 mmHg
Density 1.2±0.1 g/cm3
Flash Point -1.1±0.0 °C
Melting Point -78 °C

Industrial Applications

This fluorinated ester is primarily employed as a critical intermediate in the synthesis of active pharmaceutical ingredients. It plays a significant role in the manufacturing of non-steroidal anti-inflammatory drugs and other therapeutic agents. Specifically, it is known for its utility in the production of intermediates for COX-2 inhibitors. Beyond pharmaceuticals, it is utilized in the development of agrochemicals and specialized organic materials where fluorine incorporation is required to enhance metabolic stability or lipophilicity. Our clients value this product for its reliability in multi-step synthesis routes. It is also used in the preparation of trifluoromethyl ketones and heterocyclic compounds which are prevalent in modern drug discovery pipelines.

Safety Handling and Storage

Safety is paramount when handling fluorinated esters. This product should be managed in a well-ventilated environment with appropriate personal protective equipment including chemical-resistant gloves and safety goggles. Due to its flash point, strict adherence to fire safety regulations is necessary. Storage requirements include keeping the container tightly closed in a cool, dry, and ventilated area away from incompatible materials such as strong oxidizing agents. Our packaging is designed to prevent leakage and ensure safety during transit, typically available in 200 kg drums or customized according to client requirements.

Quality Assurance and Logistics

We maintain a robust quality management system to guarantee product integrity from production to delivery. Every shipment is accompanied by a Certificate of Analysis (COA) confirming compliance with specified parameters. Our technical team is available to provide support regarding application specifics and regulatory documentation. Proper storage in a cool, ventilated area is recommended to maintain optimal chemical stability. Our global logistics network ensures timely delivery to support your manufacturing schedules. We strive to be a reliable partner in your supply chain, offering competitive bulk pricing without compromising on quality or safety standards.