Ethyl trifluoropyruvate
- CAS No.13081-18-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Ethyl trifluoropyruvate (CAS 13081-18-0) designed for advanced organic synthesis and pharmaceutical R&D applications.
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Product Overview
Ethyl trifluoropyruvate is a highly specialized fluorinated organic ester that serves as a critical building block in modern chemical synthesis. Characterized by the presence of a trifluoromethyl group adjacent to a keto ester functionality, this compound offers unique reactivity profiles that are essential for introducing fluorine atoms into complex molecular architectures. Our facility produces this reagent under strict quality control standards to ensure consistency for demanding research and industrial processes.
As a key intermediate, it is extensively utilized in the development of novel pharmaceutical agents, particularly where metabolic stability and bioavailability are enhanced by fluorination. The compound acts as a versatile electrophile in various condensation and coupling reactions, enabling chemists to construct sophisticated heterocyclic systems and amino acid derivatives efficiently.
Technical Specifications
We maintain rigorous analytical protocols to guarantee that every batch meets or exceeds industry standards for purity and physical properties. The following table outlines the typical specifications for our commercial grade Ethyl trifluoropyruvate.
| Parameter | Specification |
|---|---|
| CAS Number | 13081-18-0 |
| Molecular Formula | C5H5F3O3 |
| Molecular Weight | 170.09 g/mol |
| Appearance | Yellow to light yellow transparent liquid |
| Density | 1.283 g/mL at 25 °C |
| Boiling Point | 42 °C |
| Flash Point | 88 °F |
| Refractive Index | n20/D 1.341 |
| Vapor Pressure | 208 mmHg at 25 °C |
| Storage Conditions | Refrigerator (2-8 °C) |
Industrial Applications
The primary utility of Ethyl trifluoropyruvate lies in its role as a precursor for bioactive molecules. In the pharmaceutical sector, it is employed in the synthesis of kinase inhibitors, protease inhibitors, and other therapeutic candidates where the trifluoromethyl moiety improves binding affinity and metabolic resistance. Additionally, this chemical is valuable in agrochemical research for developing new pesticides with enhanced environmental profiles.
Beyond life sciences, the compound finds application in materials science, contributing to the creation of advanced polymers and functional materials with specific electronic or surface properties. Its high reactivity allows for diverse synthetic transformations, making it a staple reagent in laboratories focused on organofluorine chemistry.
Storage and Handling
Proper handling is essential to maintain the integrity of this fluorinated ester. The product should be stored in a cool, dry place, ideally within a refrigerated environment to prevent degradation. Containers must be kept tightly closed when not in use to avoid moisture absorption, which can lead to hydrolysis. Personnel should adhere to standard safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles during handling.
Why Choose Our Facility
Our company is dedicated to establishing a comprehensive fluorochemical products and technology platform. We provide customers with convenient one-stop services ranging from raw material procurement to final quality control. Our integrated industrial chain covers fluorination technology research, production, storage, and application support. We commit to delivering high-quality fluorinated reagents with reliable supply chains, ensuring that your research and production timelines are met without compromise.
