Intermediates

Ethyldiisopropylamine

  • CAS No.7087-68-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Ethyldiisopropylamine (DIEA) serves as a critical non-nucleophilic base for peptide coupling and organic synthesis processes.

Request Bulk Pricing

Product Technical Details

Product Overview

Ethyldiisopropylamine, commonly known in the industry as DIEA, is a premier organic base widely utilized across pharmaceutical manufacturing and fine chemical synthesis. As a sterically hindered amine, it functions exceptionally well as a non-nucleophilic base, making it indispensable for reactions where nucleophilic interference must be minimized. Our facility produces this compound under strict quality control standards to ensure consistent performance in sensitive chemical transformations.

This chemical is particularly valued for its role in peptide synthesis, where it acts as a proton scavenger during coupling reactions. The high purity grade we supply ensures minimal side reactions, leading to higher yields and cleaner final products for our global clientele. Whether used in laboratory research or large-scale industrial production, this reagent maintains reliable physical and chemical stability.

Technical Specifications

ParameterSpecification
CAS Number7087-68-5
Molecular FormulaC8H19N
Molecular Weight129.24 g/mol
AppearanceColorless liquid
Purity (GC)≥99.0%
Density0.782 g/cm3
Boiling Point127oC
Melting Point-46oC
Flash Point6oC
Refractive Index1.457

Industrial Applications

The versatility of Ethyldiisopropylamine makes it a cornerstone in modern organic chemistry. Its primary application lies in peptide coupling reactions, often used in conjunction with carbodiimides such as DCC or EDC. In these processes, it neutralizes the acid generated during amide bond formation without participating nucleophilically, thereby preserving the integrity of the growing peptide chain.

  • Pharmaceutical Intermediate Synthesis: Used extensively in the production of active pharmaceutical ingredients (APIs).
  • Organic Catalysis: Serves as a base catalyst in various condensation and elimination reactions.
  • Polymer Chemistry: Employed in the synthesis of specialized polymers and resins.
  • Research and Development: A standard reagent in academic and industrial laboratories for method development.

Quality Assurance and Safety

We understand that consistency is key in chemical manufacturing. Every batch of Ethyldiisopropylamine undergoes rigorous gas chromatography testing to verify purity levels exceeding 99.0%. A Certificate of Analysis (COA) is provided with every shipment to document compliance with international standards. Our manufacturing process adheres to strict environmental and safety protocols to ensure product reliability.

Regarding safety, this substance is classified as a flammable liquid and should be handled with appropriate care. It must be stored in a cool, well-ventilated area away from ignition sources and incompatible materials. We recommend using standard personal protective equipment during handling. Our packaging options include 200 kg drums, with customization available to meet specific logistical requirements for global export.