Intermediates

Fumaric Acid Monomethyl Ester

  • CAS No.2756-87-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Fumaric Acid Monomethyl Ester (CAS 2756-87-8) designed for pharmaceutical synthesis. Reliable supply with full documentation.

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Product Technical Details

Product Overview

Fumaric Acid Monomethyl Ester, also known scientifically as Monomethyl fumarate, represents a critical organic building block within the pharmaceutical and fine chemical industries. This compound serves as a versatile intermediate utilized in the synthesis of complex therapeutic agents and advanced organic structures. Our facility specializes in the production of this ester with stringent quality controls to ensure consistency across batches.

As a key component in modern medicinal chemistry, this material supports the development of targeted therapies. The chemical structure features a mono-esterified fumaric acid backbone, providing unique reactivity profiles suitable for various coupling and transformation reactions. We maintain robust manufacturing capabilities to meet the demands of research laboratories and industrial scale production alike.

Key Specifications

ParameterValue
CAS Number2756-87-8
Molecular FormulaC5H6O4
Molecular Weight130.099
AppearanceWhite crystalline powder
Assay≥98.0%
Melting Point144-145°C
Density1.3±0.1 g/cm3
Boiling Point250.0±23.0 °C at 760 mmHg
Flash Point108.9±16.1 °C

Industrial Applications

This chemical intermediate is primarily employed in the pharmaceutical sector for the synthesis of active pharmaceutical ingredients (APIs). It acts as a crucial precursor in multi-step synthesis routes, particularly for kinase inhibitors and other specialized therapeutic compounds. The high purity grade ensures minimal impurity carryover into downstream processes, which is vital for regulatory compliance in drug manufacturing.

Beyond pharmaceuticals, this ester finds utility in organic synthesis research where specific functional group transformations are required. Its stability and reactivity make it a preferred choice for chemists developing new molecular entities. We support clients with technical data to facilitate integration into their specific synthesis pathways.

Quality Assurance and Packaging

Quality is paramount in our production process. Every batch undergoes rigorous testing using advanced analytical techniques such as HPLC and NMR to verify identity and purity. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing all relevant physical and chemical parameters. Our quality management system adheres to international standards to guarantee product reliability.

Standard packaging consists of 25 kg drums, ensuring safe transport and storage. However, we understand that different projects have varying requirements. Therefore, we offer flexible packaging solutions tailored to customer specifications. This adaptability allows us to serve both small-scale research initiatives and large-scale industrial manufacturing needs effectively.

Storage and Handling

To maintain optimal stability, Fumaric Acid Monomethyl Ester should be stored in a cool, ventilated place away from direct sunlight and moisture. Proper storage conditions prevent degradation and ensure the material retains its specified properties over time. Personnel handling this chemical should follow standard safety protocols, including the use of appropriate personal protective equipment. We recommend consulting the Safety Data Sheet (SDS) for detailed handling instructions and hazard information before use.