Furan-2-yl(piperazin-1-yl)methanone hydrochloride
- CAS No.60548-09-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of Prazosin hydrochloride. Available in bulk quantities with full quality documentation.
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Product Overview
Furan-2-yl(piperazin-1-yl)methanone hydrochloride is a specialized pharmaceutical intermediate characterized by its high chemical stability and reactivity. This compound features a furan ring linked to a piperazine moiety through a ketone bridge, forming a hydrochloride salt that enhances its solubility and handling properties during synthetic processes. It serves as a critical building block in the manufacturing of advanced therapeutic agents, specifically within the cardiovascular and neurological treatment sectors.
Our manufacturing facility adheres to strict quality management systems to ensure every batch meets rigorous international standards. We understand the importance of consistency in pharmaceutical synthesis, which is why our production lines are optimized for purity and reproducibility. This product is supplied exclusively to licensed chemical enterprises and research institutions for legitimate industrial and development purposes.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Furan-2-yl(piperazin-1-yl)methanone hydrochloride |
| CAS Number | 60548-09-6 |
| Molecular Formula | C9H13ClN2O2 |
| Molecular Weight | 216.67 g/mol |
| Appearance | White to off-white solid |
| Purity | ≥98.0% |
| Storage Conditions | Cool, dry, well-closed container |
Industrial Applications
The primary application of this intermediate is in the synthesis of Prazosin hydrochloride, a well-known alpha-adrenergic blocker. The structural integrity of the furan-piperazine kernel is essential for the biological activity of the final drug product. Beyond this specific pathway, the compound is valuable in medicinal chemistry research where piperazine derivatives are required for structure-activity relationship studies.
Chemists utilize this material for developing novel analogs aimed at improving therapeutic indices. Its high purity level minimizes side reactions during coupling steps, thereby increasing overall yield and reducing downstream purification costs. We support our clients with technical data packages that facilitate smooth regulatory filings and process validation.
Quality Assurance and Storage
Quality control is performed at multiple stages of production, including raw material inspection, in-process monitoring, and final product testing. Each shipment is accompanied by a Certificate of Analysis (COA) detailing test results against specified parameters. We employ advanced analytical techniques such as HPLC and NMR to verify chemical identity and potency.
To maintain product integrity, store the material in a cool and dry environment away from moisture and strong light or heat sources. The packaging consists of 25kg cardboard drums or customized containers based on client logistics requirements. Proper handling procedures should be followed to ensure safety during transfer and weighing operations. Our global logistics network ensures timely delivery while maintaining compliance with international shipping regulations for chemical goods.
