H-DL-Asp(OMe)-OMe Hydrochloride
- CAS No.14358-33-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity H-DL-Asp(OMe)-OMe hydrochloride (CAS 14358-33-9), a key chiral building block for pharmaceutical intermediates and peptide synthesis.
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Product Overview
H-DL-Asp(OMe)-OMe hydrochloride is a protected derivative of aspartic acid, widely employed as a versatile intermediate in the synthesis of complex pharmaceutical APIs and bioactive peptides. With a molecular formula of C6H12ClNO4 and a molecular weight of 197.62 g/mol, this compound features dual methyl ester protection on the carboxylic acid groups, enhancing its stability and reactivity in multi-step organic syntheses.
Specifications
| Molecular Formula | C6H12ClNO4 |
|---|---|
| Molecular Weight | 197.62 g/mol |
| CAS Number | 14358-33-9 |
| Appearance | White or Off-white Solid |
| Purity | ≥98% (by HPLC) |
| Melting Point | 115–116.5 °C (from ethanol/ethyl acetate) |
| Boiling Point | 223 °C at 760 mmHg |
| Flash Point | 88.9 °C |
Industrial Applications
This aspartic acid derivative serves primarily as a chiral synthon in advanced organic synthesis, particularly in the construction of peptidomimetics and neuroactive compounds. Its protected functional groups allow for selective deprotection strategies, making it invaluable in solid-phase peptide synthesis (SPPS) and medicinal chemistry workflows.
- Used as a building block for custom peptide sequences requiring aspartate incorporation
- Facilitates stereoselective synthesis in API development
- Suitable for research and large-scale GMP-compliant manufacturing
Handling and Storage
Store H-DL-Asp(OMe)-OMe hydrochloride at 2–8 °C in a tightly sealed container under dry, inert conditions. Protect from moisture and light to maintain chemical integrity. Standard packaging is 25 kg per drum, with customized options available upon request.
