Intermediates

Iodotrimethylsilane

  • CAS No.16029-98-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade Iodotrimethylsilane for organic synthesis. High purity ≥99.0% with reliable global supply.

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Product Technical Details

Product Overview

Iodotrimethylsilane, frequently recognized in industrial contexts as Trimethyliodosilane or TMSI, represents a critical reagent within the realm of advanced organic synthesis. This specialized silane compound is engineered to facilitate precise chemical transformations, particularly serving as a potent silylating agent and a selective deprotection reagent. Our manufacturing process ensures that every batch meets rigorous international standards for purity and consistency, making it an indispensable tool for pharmaceutical research and fine chemical production.

As a leading global manufacturer, we understand the stringent requirements of modern chemical synthesis. Iodotrimethylsilane is valued for its ability to cleave ethers and esters under mild conditions, offering chemists a reliable pathway to modify complex molecular structures without compromising sensitive functional groups. The product is supplied as a straw-colored liquid, indicating its high quality and stability when stored correctly.

Technical Specifications

Quality control is paramount in the production of fine chemical intermediates. We employ advanced gas chromatography and spectroscopic analysis to verify the composition of each lot. The following table outlines the key physical and chemical properties that define our premium grade Iodotrimethylsilane:

ParameterSpecification
CAS Number16029-98-4
Molecular FormulaC3H9ISi
Molecular Weight200.09 g/mol
AppearanceStraw liquid
Purity (GC)≥99.0%
Density1.406 g/cm³
Boiling Point106°C
Refractive Index1.471

Industrial Applications

The versatility of Iodotrimethylsilane makes it a cornerstone in the synthesis of various high-value compounds. Its primary function lies in the protection and deprotection of functional groups, a fundamental step in multi-step organic synthesis. Specifically, it is widely utilized in the preparation of pharmaceutical intermediates where precise control over reaction conditions is required.

  • Acts as a highly effective silane blocking agent in polymer chemistry.
  • Facilitates the cleavage of carbon-oxygen bonds in ether and ester functionalities.
  • Supports the development of novel therapeutic compounds through selective modification.
  • Enables efficient synthesis routes for complex organic molecules.

Quality Assurance and Safety

We are committed to delivering products that adhere to strict safety and quality protocols. Each shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with the specified parameters. Proper handling is essential due to the reactive nature of silane compounds. We recommend storing this product in a cool, ventilated area away from moisture and incompatible materials to maintain its integrity over time.

Our logistics network ensures secure packaging, typically available in 280 kg drums, with customization options to suit specific client requirements. By choosing our Iodotrimethylsilane, you gain access to a reliable supply chain backed by decades of expertise in the chemical industry. Contact our technical team today to discuss your synthesis needs and request a competitive bulk price quote.