Intermediates

Isophthaloyl Chloride

  • CAS No.99-63-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Isophthaloyl Chloride (99.96%) for industrial-scale synthesis of aramid fibers, high-performance polymers, and specialty chemicals.

Request Bulk Pricing

Product Technical Details

Product Overview

Isophthaloyl Chloride (CAS 99-63-8) is a critical aromatic diacid chloride widely employed as a high-reactivity building block in advanced polymer chemistry. This compound serves as an essential intermediate in the production of meta-aramid fibers, such as Nomex® analogs, high-temperature-resistant polyamides, and specialty engineering plastics. Its symmetrical 1,3-benzenedicarbonyl structure enables precise control over polymer chain architecture, resulting in materials with exceptional thermal stability, chemical resistance, and mechanical strength.

Specifications

Molecular FormulaC₈H₄Cl₂O₂
Molecular Weight203.02 g/mol
AppearanceWhite crystalline solid
Purity (GC)≥99.5% (Typical: 99.96%)
Water Content≤0.05% (Typical: 0.011%)
Melting Point43–44 °C
Boiling Point276 °C (lit.)
Density1.388 g/cm³
Refractive Index1.570 at 47 °C
SolubilityReacts with water; soluble in common organic solvents such as dichloromethane, THF, and acetonitrile

Industrial Applications

As a versatile bifunctional acylating agent, Isophthaloyl Chloride is indispensable in multiple high-value chemical manufacturing sectors:

  • Aramid Fiber Production: Key monomer for synthesizing meta-oriented aromatic polyamides used in flame-resistant textiles, protective gear, and electrical insulation.
  • High-Performance Polymers: Enables the fabrication of polyesters, polyketones, and polyimides with superior thermal and mechanical properties for aerospace and automotive applications.
  • Pharmaceutical & Agrochemical Intermediates: Serves as a scaffold in the construction of complex heterocyclic systems for active ingredient development.
  • Dyes and Pigments: Utilized in the synthesis of thermally stable colorants for engineering plastics and high-end coatings.

Handling and Storage

Isophthaloyl Chloride is moisture-sensitive and reacts vigorously with water, releasing hydrochloric acid. Store in a cool, dry, and well-ventilated area under inert atmosphere (e.g., nitrogen). Keep containers tightly sealed and segregated from alkalis, oxidizing agents, and sources of moisture. Use appropriate PPE including chemical-resistant gloves, goggles, and respiratory protection during handling.