L(+)-Diethyl L-Tartrate
- CAS No.87-91-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity chiral intermediate essential for asymmetric synthesis and pharmaceutical manufacturing, ensuring optimal stereochemical control.
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Product Overview
L(+)-Diethyl L-Tartrate stands as a pivotal chiral building block within the realm of advanced organic synthesis and medicinal chemistry. As a derivative of natural tartaric acid, this compound offers exceptional stereochemical integrity, making it indispensable for researchers and manufacturers focused on enantioselective processes. Our facility specializes in producing this high-value intermediate with rigorous quality controls to meet the demanding standards of the global pharmaceutical industry.
The significance of chiral auxiliaries like L(+)-Diethyl L-Tartrate cannot be overstated in modern drug development. By providing a reliable source of chirality, it enables the precise construction of complex molecular architectures. This level of precision is critical when developing active pharmaceutical ingredients where biological activity is strictly dependent on molecular handedness. We ensure every batch delivers consistent optical rotation and chemical purity.
Key Specifications
To guarantee performance in sensitive synthetic routes, we adhere to strict physical and chemical parameters. The following table outlines the standard specifications for our premium grade material:
| Parameter | Specification |
|---|---|
| CAS Number | 87-91-2 |
| Molecular Formula | C8H14O6 |
| Molecular Weight | 206.193 g/mol |
| Appearance | Colorless to light yellow transparent liquid |
| Assay (Purity) | ≥99.0% |
| Specific Rotation | +25° to +27° |
| Density | 1.204 g/cm3 |
| Boiling Point | 280 °C |
| Refractive Index | 1.445-1.447 |
| Moisture Content | ≤0.5% |
Industrial Applications
This compound serves as a critical chiral building block in the synthesis of complex antifungal agents such as Posaconazole. Beyond this specific application, it is widely utilized in Sharpless asymmetric epoxidation and other stereoselective transformations. The high optical purity ensures that downstream reactions proceed with minimal formation of unwanted enantiomers, thereby reducing waste and improving overall yield in multi-step synthesis pathways.
Manufacturers leveraging this intermediate benefit from improved process efficiency and regulatory compliance. The consistent quality supports the production of final drug substances that meet international pharmacopoeia standards. Whether used in laboratory-scale research or large-scale commercial production, our material provides the reliability needed for critical pharmaceutical projects.
Quality Assurance
Quality is the cornerstone of our manufacturing philosophy. Each production lot undergoes comprehensive testing using advanced analytical techniques including HPLC, GC, and polarimetry. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality management system is designed to trace every batch back to raw material sources, ensuring full transparency and accountability.
- Strict control over enantiomeric excess
- Regular equipment calibration and maintenance
- Comprehensive stability testing programs
- Compliance with international safety standards
Storage and Handling
To maintain optimal stability, L(+)-Diethyl L-Tartrate should be stored in a cool, ventilated place away from direct sunlight and moisture. Containers must be kept tightly closed when not in use to prevent contamination or hydrolysis. Standard laboratory safety precautions apply, including the use of appropriate personal protective equipment during handling. For bulk orders, we offer flexible packaging solutions including 200 kg drums or customized configurations based on specific logistical requirements.
