L-tert-Leucine
- CAS No.20859-02-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity L-tert-Leucine (CAS 20859-02-3) is a critical chiral building block for antiviral and protease inhibitor synthesis.
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Product Overview
L-tert-Leucine, chemically known as (S)-2-Amino-3,3-dimethylbutyric acid, stands as a vital non-proteinogenic amino acid in the realm of modern pharmaceutical synthesis. As a specialized chiral building block, this compound plays an indispensable role in the construction of complex peptide structures and active pharmaceutical ingredients (APIs). Our facility produces this intermediate under strict quality control protocols to ensure consistency and reliability for downstream chemical manufacturing processes.
The unique steric hindrance provided by the tert-butyl group makes this molecule particularly valuable in medicinal chemistry. It is frequently employed to enhance the metabolic stability and bioavailability of peptide-based therapeutics. By incorporating this bulky amino acid residue, chemists can modulate the conformational properties of drug candidates, leading to improved efficacy in treating various pathological conditions.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 20859-02-3 |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.17 g/mol |
| Appearance | White to almost white powder |
| Purity | ≥99.0% |
| Loss on Drying | ≤0.50% |
| Residue on Ignition | ≤0.50% |
| Melting Point | 300 °C |
Industrial Applications
This high-grade chemical intermediate is primarily utilized in the synthesis of protease inhibitors and antiviral agents. It serves as a key structural component in the manufacturing process of several prominent pharmaceutical products. Specifically, it acts as a crucial precursor in the production pathways for APIs used in the treatment of viral infections. The compound's stability and reactivity profile make it suitable for large-scale industrial synthesis where reproducibility is paramount.
Beyond antiviral applications, L-tert-Leucine is also explored in the development of novel peptide therapeutics. Its ability to resist enzymatic degradation allows for the design of drugs with extended half-lives. Research and development teams in the pharmaceutical sector rely on this building block to innovate next-generation treatments requiring robust peptide backbones.
Quality Assurance and Storage
We adhere to rigorous manufacturing standards to guarantee the integrity of every batch. Each production lot undergoes comprehensive analytical testing, including HPLC and NMR verification, to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to facilitate your quality control procedures. Our commitment to industrial purity ensures that the material meets the demanding requirements of API synthesis.
Proper storage is essential to maintain the chemical properties of this product. It should be kept in a cool, dry, and well-closed container, protected from moisture and strong light. Under recommended storage conditions, the material retains its specified quality attributes over an extended period. We offer flexible packaging options, including 25kg cardboard drums, to suit various logistical needs and customer specifications.
Why Choose Our Supply
- Consistent high purity levels suitable for GMP environments.
- Reliable global shipping with secure packaging solutions.
- Technical support available for synthesis route optimization.
- Competitive bulk pricing for long-term manufacturing partnerships.
- Strict compliance with international chemical safety regulations.
