Methyl 1H-1,2,4-triazole-3-carboxylate
- CAS No.4928-88-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used in antiviral synthesis. Ideal for Ribavirin production with strict quality control and global supply capabilities.
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Product Overview
Methyl 1H-1,2,4-triazole-3-carboxylate is a specialized heterocyclic compound widely recognized for its critical role in modern pharmaceutical synthesis. As a key building block, this chemical serves as an essential intermediate in the production of antiviral medications, most notably Ribavirin. Our manufacturing process ensures consistent molecular integrity, making it a preferred choice for research laboratories and large-scale pharmaceutical production facilities seeking reliable raw materials for complex organic synthesis.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 4928-88-5 |
| Molecular Formula | C4H5N3O2 |
| Molecular Weight | 127.101 |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 196-199 °C |
| Loss on Drying | ≤0.5% |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 283.9±23.0 °C at 760 mmHg |
Industrial Applications
The primary application of this triazole derivative lies within the medicinal chemistry sector, specifically for the synthesis of nucleoside analogues. Its high thermal stability, indicated by a melting point range of 196-199 °C, allows for robust processing conditions during multi-step synthesis routes. Beyond Ribavirin, this intermediate is valuable for developing other triazole-based therapeutic agents targeting viral infections. The high purity level ensures minimal side reactions, optimizing yield and reducing downstream purification costs for API manufacturers.
Quality Assurance and Packaging
We adhere to strict quality control protocols to maintain industrial purity standards. Each batch undergoes rigorous testing via High-Performance Liquid Chromatography (HPLC) to verify assay content and impurity profiles. Moisture content is tightly controlled with a loss on drying specification of ≤0.5% to prevent hydrolysis during storage. Standard packaging includes 25 kg drums, though we offer flexible customization to meet specific logistical requirements. A Certificate of Analysis (COA) is provided with every shipment to guarantee compliance with specified parameters.
Storage and Handling
To maintain chemical stability, this product should be stored in a cool, ventilated environment away from direct sunlight and moisture sources. Proper handling procedures include using appropriate personal protective equipment (PPE) to avoid inhalation or skin contact. When stored under recommended conditions, the material retains its specified properties for extended periods, ensuring readiness for immediate use in production schedules. Our global supply chain ensures timely delivery to support uninterrupted manufacturing operations.
