Intermediates

Methyl 2-Bromomethyl-3-Nitrobenzoate

  • CAS No.98475-07-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade pharmaceutical intermediate used in the synthesis of Lenalidomide. Available in bulk with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

Methyl 2-Bromomethyl-3-Nitrobenzoate is a high-value organic compound primarily utilized within the pharmaceutical industry as a critical building block. This specialized intermediate plays an essential role in the multi-step synthesis of complex therapeutic agents, including immunomodulatory drugs. Our manufacturing process ensures exceptional chemical stability and consistency, making it a reliable choice for large-scale production environments.

As a dedicated supplier of fine chemicals, we understand the stringent requirements of pharmaceutical synthesis. Each batch undergoes rigorous analytical testing to confirm identity and purity levels. The compound is characterized by its distinct structural properties, featuring a bromomethyl group and a nitro substituent on the benzoate framework, which facilitates specific nucleophilic substitution reactions required in downstream processing.

Key Specifications

Quality assurance is paramount in our production facility. We adhere to strict internal standards that often exceed general industry expectations. The following table outlines the typical physical and chemical parameters for this product:

ParameterSpecification
CAS Number98475-07-1
Molecular FormulaC9H8BrNO4
Molecular Weight274.068 g/mol
AppearanceWhite or almost white solid
Assay (Purity)≥98.5%
Moisture Content≤0.5%
Loss on Drying≤0.5%
Residue on Ignition≤1.0%
Melting Point72-74 °C
Density1.6±0.1 g/cm3

Industrial Applications

This chemical intermediate is predominantly employed in the manufacture of active pharmaceutical ingredients (APIs). Specifically, it serves as a precursor in the synthesis pathway of Lenalidomide, a medication used in the treatment of certain hematological conditions. The high purity level ensures minimal impurity carry-over into subsequent reaction steps, which is vital for meeting regulatory compliance in drug manufacturing.

Beyond its primary application, this benzoate derivative is valuable for research and development in organic synthesis laboratories. Its reactivity profile allows chemists to explore various functional group transformations, making it a versatile tool for developing new chemical entities.

Storage and Handling

To maintain product integrity, proper storage conditions are essential. The material should be kept in a cool, ventilated area away from direct sunlight and moisture sources. Containers must remain tightly sealed when not in use to prevent hydrolysis or degradation. We recommend standard laboratory safety protocols during handling, including the use of appropriate personal protective equipment.

Packaging and Supply

We offer flexible packaging solutions to meet diverse client needs. The standard package size is 25 kg per drum, ensuring safe transport and easy handling. However, we can accommodate custom packaging requirements upon request. Our logistics network supports global distribution, ensuring timely delivery with full documentation, including Certificates of Analysis (COA) and safety data sheets.