Intermediates

Methyl 3,3-Dimethoxypropionate

  • CAS No.7424-91-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Methyl 3,3-Dimethoxypropionate (CAS 7424-91-1) designed for pharmaceutical synthesis, specifically serving as a critical intermediate in Fluvastatin production.

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Product Technical Details

Product Overview

Methyl 3,3-Dimethoxypropionate is a specialized organic compound widely recognized for its pivotal role in the pharmaceutical industry. As a key building block, this chemical serves as an essential intermediate in the synthesis of various therapeutic agents, most notably within the statin class of medications. Our facility produces this compound under strict quality control measures to ensure it meets the rigorous demands of modern drug manufacturing processes. The material is characterized by its high stability and reactivity, making it an ideal candidate for complex organic synthesis routes.

We understand that consistency is paramount in pharmaceutical supply chains. Therefore, every batch of Methyl 3,3-Dimethoxypropionate undergoes comprehensive analytical testing to verify identity, purity, and physical properties. This commitment to excellence ensures that downstream manufacturers can rely on our product for consistent yield and performance in their final active pharmaceutical ingredient (API) production.

Technical Specifications

ParameterValue
CAS Number7424-91-1
Molecular FormulaC6H12O4
Molecular Weight148.157 g/mol
AppearanceColorless liquid
Assay (Purity)≥98.0%
Density1.0±0.1 g/cm3
Boiling Point178.8±0.0 °C at 760 mmHg
Flash Point65.6±0.0 °C

Industrial Applications

The primary application of Methyl 3,3-Dimethoxypropionate lies in the synthesis of Fluvastatin, a widely prescribed HMG-CoA reductase inhibitor used to manage cholesterol levels. The unique chemical structure of this ester allows for specific functional group transformations required during the multi-step synthesis of the final drug substance. Beyond statin production, this compound finds utility in broader organic chemistry applications where a protected aldehyde equivalent or specific ester functionality is required.

Our clients utilize this intermediate to streamline their manufacturing processes, benefiting from its high purity which reduces the need for extensive purification steps later in the synthesis chain. This efficiency translates to cost savings and improved overall process safety for our partners.

Quality Assurance and Storage

Quality assurance is the cornerstone of our operation. We employ advanced chromatographic and spectroscopic methods to validate each production lot. A Certificate of Analysis (COA) is provided with every shipment, detailing the specific test results against our internal specifications and international standards. This transparency allows our customers to maintain their own regulatory compliance with ease.

Regarding storage, Methyl 3,3-Dimethoxypropionate should be kept in a cool, ventilated area away from direct sunlight and sources of ignition. The product is packaged in 200 kg drums as standard, but we offer flexible packaging solutions to accommodate specific logistical requirements or smaller scale research needs. Proper handling procedures should be followed to maintain the integrity of the chemical during transport and storage.