Intermediates

Methyl 3-Aminothiophene-2-Carboxylate

  • CAS No.22288-78-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Methyl 3-Aminothiophene-2-Carboxylate (CAS 22288-78-4) serving as a critical intermediate for pharmaceutical and agrochemical synthesis.

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Product Technical Details

Product Overview

Methyl 3-aminothiophene-2-carboxylate stands as a pivotal heterocyclic building block within the modern chemical industry. Characterized by its unique thiophene ring structure substituted with an amino group and a methyl ester functionality, this compound offers exceptional versatility for organic synthesis. Our manufacturing process ensures high chemical integrity, making it an ideal candidate for complex molecular constructions. The stability of the thiophene core combined with the reactivity of the amino and ester groups allows chemists to derive a wide array of downstream products efficiently.

We prioritize purity and consistency in every batch produced. As a leading global manufacturer, we understand that the quality of raw materials directly impacts the efficacy of the final active pharmaceutical ingredients or agrochemical formulations. Therefore, our production facilities operate under strict quality management systems to guarantee that each drum meets the specified analytical standards.

Technical Specifications

The following table outlines the key physicochemical properties of this material. These parameters are critical for process engineers and research scientists when designing synthesis routes or scaling up production.

ParameterValue
CAS Number22288-78-4
Molecular FormulaC6H7NO2S
Molecular Weight157.19 g/mol
AppearanceOff-white Powder
Assay≥99.0%
Melting Point62-64 °C
Boiling Point334.6 °C
Density1.3 g/cm3
Loss on Drying≤0.5%

Industrial Applications

This chemical intermediate serves as a fundamental precursor in the synthesis of several high-value compounds. Its primary application lies within the pharmaceutical sector, specifically as a key intermediate for Tenoxicam, a widely used non-steroidal anti-inflammatory drug. The structural compatibility allows for efficient coupling reactions necessary for building the final therapeutic molecule.

Furthermore, it plays a significant role in the agrochemical industry. It is utilized in the production of Thifensulfuron, a sulfonylurea herbicide effective in controlling broadleaf weeds. Beyond these specific uses, the compound is valuable for general organic synthesis where a functionalized thiophene ring is required. Researchers appreciate its solubility profile and reactivity patterns, which facilitate various transformation reactions including amidation and esterification.

Quality Assurance and Logistics

Quality control is embedded in every stage of our supply chain. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying the assay, purity, and physical constants. We employ advanced analytical techniques such as HPLC and NMR to confirm molecular structure and impurity profiles. This commitment to transparency ensures that our partners can proceed with their synthesis workflows without unexpected delays or failures.

Packaging is designed to maintain product integrity during transit. Standard packaging consists of 25kg drums, which are sealed to prevent moisture ingress and contamination. However, we offer flexible packaging solutions tailored to specific customer requirements. For storage, we recommend keeping the container tightly closed in a cool, dry, and well-ventilated area. Proper handling ensures the material retains its specified properties over time.

Our commitment to excellence extends beyond mere compliance. We actively engage in continuous improvement of our manufacturing processes to reduce environmental impact while enhancing yield. Safety data sheets (SDS) are provided with every order to ensure safe handling in your facility. Our logistics network spans globally, ensuring timely delivery to major chemical hubs across Europe, Asia, and the Americas. Reliability is our promise, and we stand behind every kilogram shipped. Contact our sales team today for bulk pricing and detailed technical support.