Methyl 3-(Cyclopropylmethoxy)-4-Hydroxybenzoate

Product Overview

Methyl 3-(Cyclopropylmethoxy)-4-Hydroxybenzoate is a specialized organic compound serving as a critical building block in the pharmaceutical industry. Primarily recognized for its role in the synthesis of Roflumilast, a potent phosphodiesterase-4 inhibitor used in the treatment of chronic obstructive pulmonary disease (COPD), this intermediate demands exceptional purity and structural integrity. Our facility produces this compound using advanced organic synthesis techniques, ensuring consistency across large-scale batches.

As a key precursor, the chemical structure combines a benzoate ester backbone with a cyclopropylmethoxy substituent, providing the necessary reactivity for downstream coupling reactions. We understand the stringent requirements of modern drug manufacturing, which is why our production process is optimized to minimize impurities and maximize yield.

Technical Specifications

Quality assurance is paramount in pharmaceutical intermediate supply. Each batch undergoes rigorous analytical testing using HPLC and NMR spectroscopy to verify identity and purity. The physical appearance is typically a fine white powder, indicating high crystallinity and low solvent residue. Our standard specification guarantees an assay of not less than 98.0%, meeting the strict demands of API manufacturers.

Industrial Applications

The primary application of this compound is in the pharmaceutical sector, specifically as an intermediate for Roflumilast. Roflumilast is a significant therapeutic agent for managing severe COPD associated with chronic bronchitis. The efficiency of the final drug synthesis heavily relies on the quality of this starting material. Impurities at this stage can propagate through the synthesis route, affecting the safety and efficacy of the final active pharmaceutical ingredient (API).

Beyond its primary use, this benzoate derivative may serve as a valuable building block in medicinal chemistry research, particularly for developing novel anti-inflammatory agents or respiratory therapeutics. Its unique substitution pattern offers versatile reactivity for further functionalization.

Quality Assurance And Supply

We operate as a global manufacturer with a commitment to reliability. Our supply chain is robust, ensuring timely delivery of bulk quantities to partners worldwide. Every shipment is accompanied by a comprehensive Certificate of Analysis (COA), detailing all critical quality attributes. We adhere to international safety standards for storage and transportation, recommending storage in a cool, ventilated environment to maintain stability.

• Consistent high purity ≥98.0% for reliable synthesis
• Scalable production capacity for bulk requirements
• Full documentation support including COA and MSDS
• Customized packaging options available upon request
• Strict quality control protocols at every manufacturing stage

Choosing the right supplier for pharmaceutical intermediates is crucial for maintaining production schedules and regulatory compliance. Our team provides technical support to assist with integration into your specific manufacturing processes, ensuring a seamless supply of this essential chemical building block.