Methyl 3-formyl-2-nitrobenzoate
- CAS No.138229-59-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate used primarily in the synthesis of Niraparib. Available in bulk quantities with strict quality control and global shipping capabilities.
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Product Overview
Methyl 3-formyl-2-nitrobenzoate is a specialized organic compound serving as a critical building block in modern pharmaceutical synthesis. Identified by CAS number 138229-59-1, this chemical features a benzoate structure substituted with both formyl and nitro functional groups. These specific structural characteristics make it an invaluable precursor in the construction of complex heterocyclic systems found in advanced therapeutic agents. Our facility produces this intermediate under rigorous quality management systems to ensure consistency and reliability for downstream pharmaceutical manufacturing.
The compound is particularly noted for its role in the production of Poly (ADP-ribose) polymerase (PARP) inhibitors. As the pharmaceutical industry continues to advance targeted cancer therapies, the demand for high-quality intermediates like Methyl 3-formyl-2-nitrobenzoate has grown significantly. We understand the critical nature of supply chain stability in drug development and commit to providing uninterrupted supply for our global partners.
Key Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Methyl 3-formyl-2-nitrobenzoate |
| CAS Number | 138229-59-1 |
| Molecular Formula | C9H7NO5 |
| Molecular Weight | 209.16 g/mol |
| Purity | ≥98.0% |
| Appearance | White to off-white powder |
| Melting Point | 127-129°C |
Industrial Applications
The primary application of this chemical lies in the synthesis of Niraparib, a crucial medication used in the treatment of ovarian cancer and other malignancies. The nitro and formyl groups present on the aromatic ring allow for versatile chemical transformations, including reduction, condensation, and cyclization reactions. These reactions are essential steps in forming the core structure of PARP inhibitors. Beyond oncology, this intermediate may also find utility in the research and development of other novel small molecule drugs requiring similar structural motifs.
For process chemists and procurement managers, securing a reliable source of this intermediate is vital for maintaining production schedules. Our manufacturing process is optimized to minimize impurities that could affect subsequent reaction yields or complicate purification steps in the final API synthesis. We provide comprehensive technical data packages to support your regulatory filings and quality assurance protocols.
Quality Assurance and Storage
Quality is the cornerstone of our operation. Every batch of Methyl 3-formyl-2-nitrobenzoate undergoes strict analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We ensure that the physical and chemical properties meet or exceed the stated specifications before shipment. A Certificate of Analysis (COA) is provided with every order to verify compliance.
- Packaging: Standard 25 kg drums, with custom packaging available upon request.
- Storage: Store in a cool, ventilated place away from direct sunlight and moisture.
- Stability: Stable under recommended storage conditions for extended periods.
- Shipping: Global logistics network ensures timely and safe delivery.
We are committed to supporting the pharmaceutical industry with compliant, high-quality chemical intermediates. Our team is available to discuss custom synthesis requirements, bulk pricing structures, and logistical arrangements to suit your specific project needs. Contact us today to request a quote or sample for your evaluation.
