Intermediates

Methyl 4-(2-Methoxy-2-Oxoethyl)-3-Nitrobenzoate

  • CAS No.334952-07-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate for Nintedanib synthesis. Available in bulk with strict quality control and COA.

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Product Technical Details

Product Overview

Methyl 4-(2-Methoxy-2-Oxoethyl)-3-Nitrobenzoate is a critical pharmaceutical intermediate primarily utilized in the synthesis of Nintedanib, a potent kinase inhibitor used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. Our facility specializes in the large-scale production of this high-value chemical building block, ensuring consistent quality and supply chain reliability for global pharmaceutical manufacturers.

We understand the stringent requirements of the pharmaceutical industry. Therefore, every batch of Methyl 4-(2-Methoxy-2-Oxoethyl)-3-Nitrobenzoate undergoes rigorous analytical testing to meet or exceed established purity standards. Our advanced manufacturing processes are designed to minimize impurities and maximize yield, providing our partners with a cost-effective and reliable source for their API synthesis needs.

Technical Specifications

The following table outlines the key physical and chemical properties of our product. We maintain strict control over these parameters to ensure compatibility with downstream synthesis reactions.

ParameterSpecification
CAS Number334952-07-7
Molecular FormulaC11H11NO6
Molecular Weight253.21 g/mol
AppearanceLight yellow powder
Purity≥98.0%
Density1.3±0.1 g/cm3
Boiling Point369.6±32.0 °C at 760 mmHg
Flash Point162.6±27.1 °C

Quality Assurance and Applications

As a dedicated intermediate for Nintedanib production, this compound plays a vital role in the construction of the final active pharmaceutical ingredient. Our quality assurance protocol includes comprehensive testing for identity, assay, and related substances. We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for that batch.

  • High consistency suitable for multi-step organic synthesis.
  • Optimized packaging to prevent moisture absorption and degradation.
  • Scalable production capacity to meet commercial demand.
  • Strict adherence to safety and environmental regulations.

Packing and Storage

To maintain product integrity during transit and storage, Methyl 4-(2-Methoxy-2-Oxoethyl)-3-Nitrobenzoate is packaged in 25kg cardboard drums or according to specific customer requirements. The material should be stored in a cool, dry, and well-closed container, protected from moisture and strong light or heat sources. Proper storage ensures the chemical stability and longevity of the product until it is ready for use in your manufacturing process.