Methyl 4'-bromomethyl biphenyl-2-carboxylate
- CAS No.114772-38-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity pharmaceutical intermediate essential for Telmisartan synthesis, offering ≥99.0% assay and reliable global supply chain solutions for bulk manufacturing needs.
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Product Overview
Methyl 4'-bromomethyl biphenyl-2-carboxylate is a critical pharmaceutical intermediate widely recognized for its pivotal role in the synthesis of Angiotensin II receptor blockers, specifically Telmisartan. This compound features a biphenyl structure with a bromomethyl group and a methyl ester functionality, making it highly reactive and suitable for complex organic synthesis pathways. Our manufacturing process ensures exceptional chemical stability and consistency, meeting the rigorous demands of modern pharmaceutical production.
As a dedicated supplier of advanced chemical intermediates, we prioritize quality assurance at every stage of production. The compound is synthesized under strictly controlled conditions to minimize impurities and maximize yield. This commitment to excellence makes our product a preferred choice for pharmaceutical companies seeking reliable raw materials for cardiovascular medication development.
Technical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 114772-38-2 |
| Molecular Formula | C15H13BrO2 |
| Molecular Weight | 305.167 g/mol |
| Appearance | White or almost white crystalline powder |
| Assay (HPLC) | ≥99.0% |
| Single Impurity | ≤0.5% |
| Melting Point | 56 °C |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 412.8±38.0 °C at 760 mmHg |
| Flash Point | 203.5±26.8 °C |
Industrial Applications
The primary application of Methyl 4'-bromomethyl biphenyl-2-carboxylate lies in the pharmaceutical sector, serving as a key building block for Telmisartan. Telmisartan is a widely prescribed medication used to treat hypertension and reduce cardiovascular risk. The high purity of this intermediate ensures that the final active pharmaceutical ingredient meets international regulatory standards, including USP and EP monographs.
Beyond its use in antihypertensive drugs, this chemical structure offers versatility for research and development in medicinal chemistry. Scientists utilize this compound to explore new derivatives and analogs within the biphenyl carboxylic acid family. Its reactivity allows for various substitution reactions, facilitating the discovery of novel therapeutic agents targeting metabolic and cardiovascular conditions.
Quality Assurance and Safety
We implement a comprehensive quality management system to guarantee product integrity. Each batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) to verify assay purity and impurity profiles. Certificates of Analysis (COA) are provided with every shipment, ensuring full traceability and compliance with customer specifications.
Safety is paramount in handling chemical intermediates. This product should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper personal protective equipment (PPE) is recommended during handling to prevent inhalation or skin contact. Our packaging solutions are designed to maintain product stability during transit, utilizing durable drums that protect against physical damage and environmental exposure.
Why Choose Our Supply
- Consistent high purity levels exceeding 99.0% for reliable synthesis outcomes.
- Scalable production capacity to meet bulk order requirements globally.
- Comprehensive technical support and documentation for regulatory filings.
- Competitive pricing structures for long-term partnership agreements.
- Efficient logistics network ensuring timely delivery to international destinations.
Partner with us for your pharmaceutical intermediate needs and benefit from our decades of expertise in chemical manufacturing. We are committed to supporting your production goals with premium quality materials and exceptional service standards.
