Intermediates

Methyl 4-Chlorocarbonylbenzoate

  • CAS No.7377-26-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Methyl 4-Chlorocarbonylbenzoate (CAS 7377-26-6) serves as a versatile acyl chloride intermediate for pharmaceutical and polymer synthesis.

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Product Technical Details

Product Overview

Methyl 4-Chlorocarbonylbenzoate is a highly reactive organic intermediate characterized by its acyl chloride functional group. This compound plays a pivotal role in modern organic synthesis, particularly within the pharmaceutical and fine chemical industries. As a derivative of terephthalic acid, it offers unique reactivity profiles that enable efficient nucleophilic substitution reactions. Our manufacturing process ensures consistent quality, making it an ideal choice for complex molecular constructions where precision and purity are paramount.

The chemical structure combines a methyl ester group with a reactive chlorocarbonyl moiety on a benzene ring. This dual functionality allows chemists to selectively modify either end of the molecule, providing significant flexibility in synthetic route design. Whether used for introducing specific aromatic structures or modifying polymer chains, this intermediate delivers reliable performance under standard reaction conditions.

Technical Specifications

ParameterValue
CAS Number7377-26-6
Molecular FormulaC9H7ClO3
Molecular Weight198.60 g/mol
Purity (HPLC)≥98.0%
AppearanceOff-white to white crystalline powder
Melting Point50-59°C
Boiling Point140°C
Density1.291 g/cm³

Industrial Applications

This acyl chloride derivative is extensively utilized as a building block in the synthesis of active pharmaceutical ingredients (APIs). Its ability to form amide and ester bonds makes it indispensable for creating complex drug molecules. Additionally, it serves as a key component in the production of specialized polymers and agrochemicals. The high reactivity of the chlorocarbonyl group facilitates efficient coupling reactions, reducing overall process time and improving yield rates in large-scale manufacturing.

  • Pharmaceutical intermediate for API synthesis
  • Polymer modification and cross-linking agent
  • Agrochemical formulation component
  • Fine chemical synthesis building block

Quality Assurance and Safety

We adhere to strict quality control protocols to ensure every batch meets international standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity, identity, and physical properties. Given its classification as a corrosive substance (Hazard Class 8), proper handling procedures are essential. The product should be stored in a cool, dry place away from moisture and incompatible materials. Our packaging solutions are designed to maintain stability during global transit, ensuring the material arrives in optimal condition for your production needs.