Methyl 5-acetyl-2-phenylmethoxybenzoate
- CAS No.27475-09-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity Methyl 5-acetyl-2-phenylmethoxybenzoate (CAS 27475-09-8) serves as a critical pharmaceutical intermediate for Salmeterol synthesis, available in bulk quantities with full COA.
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Product Overview
Methyl 5-acetyl-2-phenylmethoxybenzoate is a specialized organic compound widely recognized for its pivotal role in the pharmaceutical industry. As a key building block, this chemical intermediate is essential for the synthesis of advanced therapeutic agents, particularly in the development of respiratory medications. Our facility produces this compound under strict quality control protocols to ensure consistency and reliability for downstream manufacturing processes.
The molecular structure features a benzoate core with acetyl and phenylmethoxy substituents, providing the necessary reactivity for complex organic transformations. This high-performance intermediate is designed to meet the rigorous demands of modern drug synthesis, offering excellent stability and solubility characteristics required for multi-step reaction pathways.
Chemical Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 27475-09-8 |
| Molecular Formula | C17H16O4 |
| Molecular Weight | 284.31 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | ≥98.0% |
| Density | 1.167 g/cm3 |
| Boiling Point | 443.48 °C at 760 mmHg |
| Flash Point | 196.82 °C |
Industrial Applications
The primary application of Methyl 5-acetyl-2-phenylmethoxybenzoate is in the synthesis of Salmeterol, a long-acting beta-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease (COPD). Its high purity level ensures minimal impurity carry-over into the final active pharmaceutical ingredient (API), which is critical for regulatory compliance and patient safety.
Beyond respiratory therapeutics, this intermediate serves as a versatile precursor in medicinal chemistry research. It is utilized in the development of novel analogues and derivatives where the benzyl ether and acetyl functionalities are required for specific biological activity. Our production process optimizes the yield and purity, making it a cost-effective choice for large-scale pharmaceutical manufacturing.
Quality Assurance and Storage
We adhere to international quality standards to guarantee the integrity of every batch. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. Our quality control team employs advanced analytical techniques, including HPLC and NMR spectroscopy, to verify identity and purity levels.
- Packaged in 25 kg drums or customized containers based on client requirements.
- Stored in a cool, ventilated environment to maintain stability.
- Protected from moisture and direct sunlight during transportation.
- Global logistics support ensures timely delivery to manufacturing sites.
For technical inquiries or bulk procurement requests, our sales team is ready to provide detailed specifications and competitive pricing structures tailored to your production needs.
